Novel glucagon-like peptide-1 drugs designed for type 2 diabetes

Novel glucagon-like peptide-1 (GLP-1) drugs were designed and industrially prepared by researchers at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences through molecular design, strain construction, ...

Breast cancer cells use force to open channels through tissue

Researching how cancers grow and spread has conventionally been done on two-dimensional, flat cultures of cells, which is very different to the three-dimensional structure of cells in the body. 3D cell cultures that incorporate ...

Competition among worm sperm speeds up evolution

From elaborate dances to stunning plumage displays to dramatic head-butting, male animals have an array of ways to distinguish themselves from competitors while wooing a potential mate. But it's not their only chance to prove ...

Protein domain structures affect the quality of stem cells

The original iPS cells were reprogrammed by transducing four genes: OCT3/4, SOX2, KLF4, and c-MYC. Later experiments would show that c-MYC can be replaced with MYCL. Both are MYC proteins and thus oncogenes, but animal experiments ...

An unusual molecule protects nerve cells from degeneration

An international research team led by Professor Stephanie Grond from the Institute of Organic Chemistry at the University of Tübingen has found that the natural substance collinolactone reduces artificially-induced stress ...

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