Scientists from Rice University are using fluorescence lifetime to shed new light on a peptide associated with Alzheimer's disease, which the Centers for Disease Control and Prevention estimates will affect nearly 14 million ...
Biochemistry
Jan 25, 2023
0
32
A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein from canine mammary tumors. This amyloid protein, α-S1 casein, normally plays a vital ...
Molecular & Computational biology
Jan 24, 2023
0
7
Stains that make specific components of a live cell light up under a microscope have become powerful tools for detecting disease and monitoring biological processes, but the choice of available stains is severely limited ...
Biochemistry
Dec 12, 2022
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48
Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between ...
Bio & Medicine
Aug 29, 2022
0
138
Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the result of minute deviations ...
Biochemistry
Jul 20, 2022
0
15
Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia. In a new study, published July 9, 2022 ...
Evolution
Jul 18, 2022
0
503
Protein function and activity are determined by both their assembly and secondary structure. Abnormalities related to either protein aggregation or secondary structure can lead to neurodegenerative diseases. In a new study, ...
Bio & Medicine
Jul 14, 2022
0
10
It is now possible to deliver therapeutics based on short interfering RNAs to hepatocytes; however, new delivery solutions are necessary to target additional organs. In a new report now published in Nature Biotechnology, ...
Researchers have shown that aggregation of amyloid-beta, one of two key proteins implicated in Alzheimer's disease, causes cells to overheat and "fry like eggs."
Biochemistry
May 31, 2022
0
252
In a finding that has important ramifications for neurodegenerative disorders such as Alzheimer's disease, RIKEN researchers have discovered how three chaperone molecules in yeast cells work together to break up beta-sheet-rich ...
Biochemistry
May 26, 2022
0
91
