A new approach makes liquid-crystal-like beacons out of harmful amyloid proteins present in diseases such as Type II diabetes.
Optics & Photonics
Feb 26, 2021
0
28
Alzheimer's disease and Parkinson's disease are both examples of amyloid diseases, where malfunctioning proteins accumulate to form fibrils and larger aggregates called amyloid plaques. In the journal Biophysical Chemistry ...
Biochemistry
Dec 10, 2020
0
8
A research team lead by Ludmilla Morozova Roche at Umeå University, Sweden, has provided the mechanistic insight into protein co-aggregation in Alzheimer's disease. The templating mechanism of S100A9 amyloids on Aβ fibrillar ...
Biochemistry
Jun 26, 2020
0
6
Neurodegenerative diseases such as Alzheimer's and Parkinson's are often accompanied by amyloid proteins in the brain that have become clumped or misfolded. A newly developed technique that measures the orientation of single ...
Optics & Photonics
Jun 4, 2020
0
108
EPFL scientists have developed powerful tools to unmask the diversity of amyloid fibrils, which are associated with Alzheimer's disease and other neurodegenerative disorders. The scientists made the breakthrough by developing ...
Bio & Medicine
Mar 12, 2020
0
57
In megacities around the world, including Mexico City, Jakarta, New Delhi, Beijing, Los Angeles, Paris and London, humans are polluting air at a rate that Earth can no longer sustain.
Environment
Sep 26, 2019
2
29
A hallmark of age-related diseases such as Parkinson's disease, type 2 diabetes, or Alzheimer's disease is the abnormal clumping of proteins in cells. In people with these conditions, these protein clumps can result in irregular ...
Biochemistry
Sep 16, 2019
0
25
A team of researchers from Durham University in the U.K. and Shaanxi Normal University in China has discovered a type of protein that forms naturally into two main types of helical braids. In their paper published in the ...
Alzheimer's disease is caused by aggregates of amyloid-β (Aβ) peptides. This aggregation is accelerated at the cell membrane surface. Using molecular dynamics simulations and NMR experiments, the research group at ExCELLS ...
Biochemistry
Jan 2, 2019
0
108
A new method of selectively binding proteins to nanoparticles has been described by a team of German and Chinese researchers headed by Prof. Bart Jan Ravoo, a chemist at the University of Münster (Germany). The nanoparticles ...
Biochemistry
Nov 21, 2018
0
45
