Protein domain structures affect the quality of stem cells

The original iPS cells were reprogrammed by transducing four genes: OCT3/4, SOX2, KLF4, and c-MYC. Later experiments would show that c-MYC can be replaced with MYCL. Both are MYC proteins and thus oncogenes, but animal experiments ...

Using math to calculate the path of cancer

Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems. Originally created ...

Machine learning discovers new sequences to boost drug delivery

Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...

Protein's 'silent code' affects how cells move

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% ...

The very venomous caterpillar

The venom of a caterpillar, native to South East Queensland, shows promise for use in medicines and pest control, Institute for Molecular Bioscience researchers say.

How chemists are building molecular assembly lines

Four huge robot arms surround the gleaming metal shell of what will soon be a top-of-the-range automobile. They jerk into life, attaching the bonnet, the wing mirrors, and other panels. It's the kind of precision operation ...

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