AI technology generates original proteins from scratch

Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino ...

Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

Artificial intelligence makes enzyme engineering easy

You can't move a pharmaceutical scientist from a lab to a kitchen and expect the same research output. Enzymes behave exactly the same: They are dependent upon a specific environment. But now, in a study recently published ...

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