Researchers shed light on how proteins find their shapes

(PhysOrg.com) -- Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show ...

Evolution provides clue to blood clotting

A simple cut to the skin unleashes a complex cascade of chemistry to stem the flow of blood. Now, scientists at Washington University School of Medicine in St. Louis have used evolutionary clues to reveal how a key clotting ...

Cell: Protein folding via charge zippers

Membrane proteins are the "molecular machines" in biological cell envelopes. They control diverse processes, such as the transport of molecules across the lipid membrane, signal transduction, and photosynthesis. Their shape, ...

New insights to the function of molecular chaperones

(Phys.org)—Heidelberg molecular biologists have gained new insights into the function of so-called molecular chaperones in protein synthesis. The team headed by Dr. Günter Kramer and Prof. Dr. Bernd Bukau of the DKFZ-ZMBH ...

Gently unfolding proteins to watch them refold

(PhysOrg.com) -- How does a protein chain fold into the same 3-D shape each time and not something disfunctional or dangerous? A new study shows that the first fold is critical. The finding by Susan Marqusee and Carlos Bustamante ...

Mutating Ebola's key protein may stop replication

Researchers may be able to stop the replication of Ebola virus by mutating its most important protein, according to a paper published in the Journal of Biological Chemistry.

Researchers piece together how proteins fold

(Phys.org) -- A new method for looking at how proteins fold inside mammal cells could one day lead to better flu vaccines, among other practical applications, say Cornell researchers.

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