Mice (and possibly humans) make their own morphine

(PhysOrg.com) -- New research has confirmed that mice have the biochemical pathways required to manufacture morphine from intermediates. Morphine is a powerful drug usually derived from the opium poppy, but scientists have ...

Chemists synthesize fungal compound with anti-cancer activity

(PhysOrg.com) -- Ten years ago, William Fenical of the Scripps Institution of Oceanography isolated from an ocean-living fungus a compound that has since shown the ability to kill cancer cells in the lab. Now, for the first ...

New way of synthesizing organic chemicals mimics nature

Organic chemists have found a new way of synthesizing multiple complex organic molecules that until now have needed to be synthesized using time-consuming methods. The new strategy, which mimics natural biosynthesis methods, ...

Micro-frog springs toxic surprise

A "robber frog" whose body is just 10 millimetres (three-eighths of an inch) long eats toxic mites and exudes their poison on its skin to deter predators, scientists reported on Wednesday.

Using poison-frog compounds to control fire ants

Since its accidental introduction into the United States from South America in the 1930s, the red imported fire ant, Solenopsis invicta, has spread throughout the southern United States, decimating small-animal populations, ...

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Alkaloid

Alkaloids are naturally occurring chemical compounds containing basic nitrogen atoms. The name derives from the word alkaline and was used to describe any nitrogen-containing base. Alkaloids are produced by a large variety of organisms, including bacteria, fungi, plants, and animals and are part of the group of natural products (also called secondary metabolites). Many alkaloids can be purified from crude extracts by acid-base extraction. Many alkaloids are toxic to other organisms. They often have pharmacological effects and are used as medications, as recreational drugs, or in entheogenic rituals. Examples are the local anesthetic and stimulant cocaine, the stimulant caffeine, nicotine, the analgesic morphine, or the antimalarial drug quinine. Some alkaloids have a bitter taste.

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