Time makes histone H3 modifications drift in mouse liver
Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.
Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.
Molecular & Computational biology
Jun 30, 2022
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6
A new editorial paper titled "WRNing for the right DNA repair pathway choice" has been published in Aging .
Molecular & Computational biology
Jun 16, 2022
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7
Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, Buck Institute scientists have discovered a new mechanism of how mitochondria start to go wrong, ...
Cell & Microbiology
May 19, 2022
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53
Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components. The findings, published in Current Biology, describe ...
Cell & Microbiology
Jun 18, 2021
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734
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Biotechnology
Dec 21, 2020
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41
Research findings by a KAIST team provide insight into the complex mechanism of cellular senescence and present a potential therapeutic strategy for reducing age-related diseases associated with the accumulation of senescent ...
Cell & Microbiology
Nov 30, 2020
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173
Molecules that accumulate at the tip of chromosomes are known to play a key role in preventing damage to our DNA. Now, researchers at EPFL have unraveled how these molecules home in on specific sections of chromosomes—a ...
Cell & Microbiology
Oct 14, 2020
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252
In a study of gorilla skeletons collected in the wild, Johns Hopkins Medicine researchers and their international collaborators report that aging female gorillas do not experience the accelerated bone loss associated with ...
Plants & Animals
Sep 30, 2020
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53
As time passes, our fertility declines and our bodies start to fail. These natural changes are what we call aging.
Plants & Animals
Aug 11, 2020
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266
Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists.
Molecular & Computational biology
Jul 16, 2020
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516