Decoding cells to unlock stem cells' potential

Stem cells are jacks of all trades, capable of alleviating the consequences of such diverse pathologies as heart attacks, strokes and cancer. However, stem cell therapies have been hampered by possible side effects, which ...

Growing embryonic tissues on a chip

It's no surprise that using human embryos for biological and medical research comes with many ethical concerns. Correct though it is to proceed with caution in these matters, the fact is that much science would benefit from ...

New understanding of worm stem cells could lead to human therapies

Research from Oxford University published today in the journal Genome Research has found that a special combination of epigenetic modifications crucial to stem cell growth evolved in animals much earlier than previously appreciated. ...

Finding a weak link in the frightful parasite Schistosoma

The parasitic disease schistosomiasis is one of the developing world's worst public health scourges, affecting hundreds of millions of people, yet only a single, limited treatment exists to combat the disease.

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Adult stem cell

Adult stem cells are undifferentiated cells, found throughout the body after embryonic development, that multiply by cell division to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells (from Greek Σωματικóς, meaning of the body), they can be found in juvenile as well as adult animals and humans.

Scientific interest in adult stem cells has centered on their ability to divide or self-renew indefinitely, and generate all the cell types of the organ from which they originate, potentially regenerating the entire organ from a few cells. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not considered to be controversial as they are derived from adult tissue samples rather than destroyed human embryos. They have mainly been studied in humans and model organisms such as mice and rats.

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