The first line of defense in our immune systems are white blood cells, 40% to 70% of which are neutrophils. These cells rush to sites of injury or infection, producing proteins to promote inflammation and attack invading ...
Biochemistry
Oct 2, 2023
0
48
A chemical modification of messenger RNA (mRNA) performs different functions depending on its location, according to a study published in the journal Molecular Cell.
Cell & Microbiology
Jul 6, 2022
0
7
Natural compounds often have promising therapeutic potential but using them to treat diseases is hampered due to toxicity or non-desirable effects. Now, a new study led by Gonçalo Bernardes, group leader at the Instituto ...
Biochemistry
Jun 27, 2022
6
94
Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit ...
Biochemistry
Nov 22, 2018
0
70
A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU), in collaboration with scientists from Tsinghua University in China, the Rockefeller University, and the University ...
Biochemistry
Nov 7, 2018
0
68
Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme ...
Biochemistry
Sep 6, 2018
0
47
UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
Biotechnology
Jul 20, 2018
0
409
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called ...
Biochemistry
Oct 31, 2017
0
25
Many things go wrong in cells during the development of cancer. At the heart of the chaos are often genetic switches that control the production of new cells. In a particularly aggressive form of leukemia, called acute myeloid ...
Biochemistry
May 22, 2017
0
112
A new study led by scientists at The Scripps Research Institute (TSRI) and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.
Biochemistry
Dec 21, 2015
0
817
