CRISPR-based tool maps gene function in human cells
UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
Biotechnology
Jul 20, 2018
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409
Scientists at The Wistar Institute have characterized a novel function for the INTS13 protein that is part of a large protein complex regulating gene transcription, called Integrator. According to study results, published ...
Cell & Microbiology
Jun 28, 2018
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0
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called ...
Biochemistry
Oct 31, 2017
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25
Many things go wrong in cells during the development of cancer. At the heart of the chaos are often genetic switches that control the production of new cells. In a particularly aggressive form of leukemia, called acute myeloid ...
Biochemistry
May 22, 2017
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112
Robert "Bob" Paine, an influential ecologist best known for introducing the concept of "keystone species" and who nurtured a generation of scientists, has died. He was 83.
Other
Jun 15, 2016
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7
A new study led by scientists at The Scripps Research Institute (TSRI) and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.
Biochemistry
Dec 21, 2015
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817
For graduate student Abe Weintraub, the magic and intrigue of DNA is all in the packaging.
Cell & Microbiology
Oct 27, 2015
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20
Rice University scientists have developed a big data technique that could have a significant impact on health care.
Computer Sciences
Aug 12, 2015
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213
Imagine having a complete catalog of the best drug targets to hit in a particularly deadly form of cancer. Imagine having a master catalog of such targets for all the major cancer types and subtypes. Scientists at Cold Spring ...
Biotechnology
May 11, 2015
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56
Researchers at UC Santa Barbara have discovered a molecular pathway that may explain how a particularly deadly form of cancer develops. The discovery may lead to new cancer therapies that reprogram cells instead of killing ...
Biochemistry
Jan 30, 2012
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