Therapeutic proteins are protein-based drug candidates bioengineered in the lab for pharmaceutical and clinical applications. Based on their pharmacokinetics, the candidates can be divided into groups that (1) replace a defective ...
(Phys.org)—Every great structure, from the Empire State Building to the Golden Gate Bridge, depends on specific mechanical properties to remain strong and reliable. Rigidity—a material's stiffness—is of particular importance ...
Nanophysics
Feb 11, 2013
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0
Our DNA contains four types of molecules, adenine, cytosine, thymine, and guanine—called nucleotides or bases—running along the strands that make up our chromosomes. Since there are only four, it is not unusual to find ...
Cell & Microbiology
Jan 11, 2023
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107
The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals—and how they can ...
Molecular & Computational biology
Aug 23, 2021
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147
Scientists at the University of Wisconsin-Madison have developed a way to use a cell's own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs.
Biochemistry
Mar 18, 2021
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54
In a multi-group collaborative involving the National Emerging Infectious Disease Laboratories (NEIDL), the Center for Regenerative Medicine (CReM), and the Center for Network Systems Biology (CNSB), scientists have reported ...
Cell & Microbiology
Dec 2, 2020
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81
Walter and Eliza Hall Institute researchers have made a surprise discovery about how subtle changes in the way cell survival is regulated during embryonic development can have drastic health implications.
Cell & Microbiology
Sep 19, 2018
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19
Scientists at Albert Einstein College of Medicine of Yeshiva University and their international collaborators have developed a novel fluorescence microscopy technique that for the first time shows where and when proteins ...
Cell & Microbiology
Mar 19, 2015
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40
Deep inside the brains of people with dementia and Lou Gehrig's disease, globs of abnormal protein gum up the inner workings of brain cells – dooming them to an early death.
Biochemistry
Jul 3, 2014
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0
Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral ...
Biotechnology
Jun 1, 2012
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