https://phys.org/ en-us Latest news from Tokyo University of Agriculture and Technology A collaborative research team has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan. Natural products often exhibit multifaceted biological activities due to their structural complexity, interacting transiently with multiple biomolecules. Yaku'amide B was previously shown to inhibit ATP synthase, an essential enzyme for cellular energy production. However, this alone could not fully explain its unique anticancer properties. https://phys.org/news/2026-03-deep-sea-natural-compound-cancer.html Biochemistry Sat, 14 Mar 2026 15:00:03 EDT news692458374 A research team from Japan has developed a unified model to scale the transitional pressure development in a one-dimensional flow. This achievement provides a better understanding of how pressure fields build up in the confined fluid system for various acceleration situations, which might be applicable to biomechanics-related impact problems, such as human brain injuries caused by physical contact. https://phys.org/news/2025-01-scales-pressure-fluctuation-liquid.html General Physics Wed, 29 Jan 2025 16:09:59 EST news657389394 The impact of a drop on a solid surface is an important phenomenon that has various applications. Especially when the drop splashes, it can cause deterioration of printing and paint qualities, erosion, and propagation of airborne virus, among others. Therefore, it is important to observe and understand the characteristics of the splashing drops of different liquids. https://phys.org/news/2024-12-ai-deciphers-splashing-patterns-high.html Soft Matter Fri, 27 Dec 2024 05:41:10 EST news654500465 Premenstrual syndrome (PMS) is a relatively common condition that affects most women who menstruate, at some point in their lives. Typically, PMS can cause a variety of symptoms, including mood swings, irritability, bloating, and fatigue. Moreover, PMS tends to worsen the symptoms of certain psychiatric and personality disorders. In certain instances, PMS can lead to premenstrual dysphoric disorder (PMDD), a type of severe depressive disorder that impairs daily life activities and interpersonal relationships. https://medicalxpress.com/news/2024-01-high-school-students-neurodevelopmental-disorders.html Obstetrics & gynaecology Wed, 10 Jan 2024 17:32:03 EST news624130321 Veterinary researchers have used organoids—three-dimensional organ-like structures grown from stem cells and tissue samples—to investigate the biological processes of lung cancer in dogs, a disease that is much rarer in our canine friends than it is in humans, but often far more deadly https://phys.org/news/2023-09-3d-organoids-insights-lung-cancer.html Cell & Microbiology Tue, 26 Sep 2023 11:58:08 EDT news614948240