https://phys.org/ en-us Latest news from The Geisel School of Medicine at Dartmouth Very early exposure to even a very small dose of herpes simplex virus (HSV) in infant mice can lead to cognitive decline later in life, according to findings from a new Dartmouth-led study, in collaboration with Harvard Medical School and published in the journal PLOS Pathogens. This is significant because of emerging data in human studies showing an association between HSV and Alzheimer's disease in humans. https://medicalxpress.com/news/2025-02-neonatal-herpes-simplex-virus-infections.html Diseases, Conditions, Syndromes Wed, 19 Feb 2025 11:13:04 EST news659185981 Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health. CF is a multi-organ genetic disease that causes sticky mucus to build up in the lungs and digestive system, as well as heightened inflammation in the gut and at other body sites. https://medicalxpress.com/news/2025-02-stalled-microbiomes-reveals-cystic-fibrosis.html Pediatrics Thu, 13 Feb 2025 12:50:48 EST news658673439 Findings from a new study, led by researchers at Dartmouth's Geisel School of Medicine and published in Nature Immunology, have uncovered key functional differences in macrophages—a type of white blood cell that plays a pivotal role in the body's innate (general) immune system as a first-line defender against pathogens. https://medicalxpress.com/news/2024-05-reveals-hidden-diversity-innate-immune.html Immunology Thu, 02 May 2024 04:01:36 EDT news633841289 Findings from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and published in the journal mBio reflect the important role that the gut microbiome (communities of bacteria) plays in the airway health of persons with cystic fibrosis. https://medicalxpress.com/news/2024-03-important-role-gut-microbes-play.html Diseases, Conditions, Syndromes Wed, 13 Mar 2024 14:32:54 EDT news629559169 Findings from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and Thayer School of Engineering and published in Cell Reports Medicine offer new insights into how antibodies function in combating herpes simplex virus (HSV) infections. The research may lead to possible new treatments for neonatal herpes. https://medicalxpress.com/news/2024-02-insights-antibodies-function-herpes-simplex.html Diseases, Conditions, Syndromes Mon, 12 Feb 2024 16:32:03 EST news626977921 Results from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and Harvard Medical School/Brigham and Women's Hospital, published in the August issue of Health Affairs, show that a substantial portion—nearly half—of low-value care received by Medicare beneficiaries happens outside of their health systems. https://medicalxpress.com/news/2023-08-impact-low-value-medicare-beneficiaries-health.html Medical economics Tue, 08 Aug 2023 06:26:15 EDT news610694771 Findings from an innovative study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and published in the journal Social Science & Medicine are providing new insights into how the rapid spread (or diffusion) of fraudulent Medicare home health care billing has occurred across the U.S. in recent years. https://medicalxpress.com/news/2023-06-insights-medicare-fraud-regions-years.html Medical economics Thu, 08 Jun 2023 16:53:36 EDT news605462009 At the core of the U.S. health care system there is a paradox, says Elliott Fisher, MD, MPH, a professor of health policy, medicine, and community and family medicine at The Dartmouth Institute for Health Policy and Clinical Practice. https://medicalxpress.com/news/2023-04-qa-high-greed-health.html Medical economics Tue, 18 Apr 2023 17:38:04 EDT news601058282 As Americans, we've become accustomed to the nearly unique experience of seeing commercials for medicines like prescription drugs on television—only the U.S. and New Zealand allow this kind of direct-to-consumer (DTC) advertising. https://medicalxpress.com/news/2023-04-qa-potential-benefits-multi-cancer-early.html Oncology & Cancer Tue, 11 Apr 2023 16:30:01 EDT news600448244 Findings from a new study published in The Clinical Journal of the American Society of Nephrology, involving a collaborative effort between researchers at Dartmouth's Geisel School of Medicine, Vanderbilt, and Veteran's Affairs (VA) medical centers, show that an implementation science approach using team-based coaching and automated surveillance reporting significantly reduces the risk of acquiring post-procedural acute kidney injury (AKI) when compared to other interventions. https://medicalxpress.com/news/2023-01-team-based-acute-kidney-injury-heart.html Diseases, Conditions, Syndromes Thu, 19 Jan 2023 16:10:35 EST news593367032 Findings from a new study published in Cell Reports, involving a collaborative effort between researchers at the Luikart Laboratory at Dartmouth's Geisel School of Medicine and the Weston Laboratory at the University of Vermont, are providing further insight into the neurobiological basis of autism spectrum disorders (ASD) and pointing to possible treatments. https://medicalxpress.com/news/2022-11-insights-genetic-mutations-autism-disorders.html Genetics Tue, 01 Nov 2022 12:53:03 EDT news586525981 Published today in PLOS ONE, "Serial T-SPOT.TB responses in Tanzanian adolescents: transient, persistent and irregular conversions," investigators from the Geisel School of Medicine and Muhimibili University of Health and Allied Sciences (MUHAS) report high rates of new tuberculosis (TB) infection among adolescents in Tanzania. Multiple blood tests for TB infection were conducted over three years in 650 schoolchildren age 13-15 and showed that the risk of acquiring new TB infection was 3 percent per year. In addition, by performing six or more blood tests on each volunteer with an interferon gamma release assay (IGRAs) the study team identified new patterns of transition between positive and negative IGRA tests for TB infection. https://medicalxpress.com/news/2022-06-team-tuberculosis-infection-adolescents-tanzania.html Diseases, Conditions, Syndromes Fri, 24 Jun 2022 15:54:10 EDT news575304845 Findings from a new study, led by researchers at Dartmouth's Geisel School of Medicine and published in JAMA Neurology, show that higher death rates have been associated with the COVID-19 pandemic among older adults with cognitive impairment—especially in racial and ethnic minority populations and those living in nursing homes. https://medicalxpress.com/news/2022-02-higher-death-older-adults-cognitive.html Alzheimer's disease & dementia Mon, 28 Feb 2022 13:00:01 EST news565275201 A new study by researchers at Dartmouth, Carnegie Mellon University, the University of Pittsburgh, and the Lisa Schwartz Foundation for Truth in Medicine, published this week in JAMA Internal Medicine, shows that people using COVID home test kits may fail to self-quarantine or may quarantine unnecessarily because they misinterpret the implications of test results. https://medicalxpress.com/news/2022-01-consumers-results-at-home-covid-.html Diseases, Conditions, Syndromes Mon, 31 Jan 2022 11:09:01 EST news562849738 Findings from a new study conducted jointly at Dartmouth's Geisel School of Medicine and Harvard Medical School, and published in Health Services Research, highlight the statistical drawbacks of one form of analysis commonly used in health services research while demonstrating the benefits of another. https://medicalxpress.com/news/2021-11-reveals-flaws-statistical-approach-health.html Medical research Wed, 17 Nov 2021 15:50:39 EST news556386632 A new Dartmouth-led study published in Pediatric Research has found a direct and sex-specific association between the composition of infant microbiome and early childhood behavioral health. https://medicalxpress.com/news/2021-11-insights-infant-microbiome-impacts-early.html Pediatrics Thu, 04 Nov 2021 13:00:05 EDT news555249599 A new Dartmouth-led study published this month in the New England Journal of Medicine sheds light on the role U.S. health systems play concerning racial inequality in prescription pain medicine receipt. https://medicalxpress.com/news/2021-07-explores-inequity-opioid-health.html Medications Wed, 21 Jul 2021 17:00:01 EDT news546091440 A new Dartmouth-led study, published this week in the journal Pediatrics, has found that the disproportionate use of premiums within child-targeted TV advertising for children's fast-food meals is deceptive. The researchers examined thousands of advertisements from 11 fast-food restaurants, but one company—McDonald's—accounted for nearly all the airtime and, as a result, the findings. https://medicalxpress.com/news/2021-05-overemphasis-toy-giveaways-tv-ads.html Overweight & Obesity Mon, 10 May 2021 12:15:30 EDT news539867711 Findings from a new Geisel-led study, published in the Journal of General Internal Medicine, reveal that there is substantial variation across different regions of the country in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, and that areas with greater use of these prescription drugs experience higher hip fracture rates. https://medicalxpress.com/news/2021-02-variation-intensity-fracture-associated-prescription-drug.html Medications Tue, 16 Feb 2021 16:40:34 EST news532716030 A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington (UW) and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet (UV) light can worsen clinical symptoms in autoimmune diseases such as lupus. https://medicalxpress.com/news/2021-01-reveals-insights-link-sunlight-exposure.html Diseases, Conditions, Syndromes Thu, 21 Jan 2021 16:38:09 EST news530469484 A new article, published in the American Journal of Preventive Medicine by a team of researchers and advocates including Dartmouth faculty, asserts that current gaps in the regulation of commercial educational websites are exposing children to unhealthy food marketing. https://medicalxpress.com/news/2020-12-child-directed-food-websites.html Health Thu, 10 Dec 2020 16:03:56 EST news526838634 Results from a new study co-led by researchers at Dartmouth's Geisel School of Medicine and the Department of Surgery at Kuma Hospital in Kobe, Japan show that active surveillance can be successfully implemented as a viable treatment option for patients with low-risk thyroid cancer. The study is the first to specifically analyze patient retention and adherence in an active surveillance program for thyroid cancer. https://medicalxpress.com/news/2020-12-surveillance-treatment-option-low-risk-thyroid.html Oncology & Cancer Tue, 08 Dec 2020 12:50:01 EST news526654197 Findings from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and published in the journal Preventive Medicine Reports, show that involving pediatric practices in the promotion of private well water testing can influence parental compliance. https://medicalxpress.com/news/2020-10-pediatric-primary.html Health Mon, 26 Oct 2020 14:32:38 EDT news522941555 Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine. The three-year trial was conducted among 650 adolescents in Tanzania, a nation with high rates of TB infection, and showed that the vaccine was safe and induced immune responses against the disease. https://medicalxpress.com/news/2020-09-successful-tb-vaccine-phase-trial.html Diseases, Conditions, Syndromes Tue, 29 Sep 2020 12:07:06 EDT news520600023 A Dartmouth-led study, published in the journal Pediatrics, offers new details about pediatric mental health boarding in emergency departments across the country, a problem that has steadily increased in the last 10 years and been made worse by a shortage of psychiatric resources. https://medicalxpress.com/news/2020-09-pediatric-mental-health-boarding.html Psychology & Psychiatry Fri, 25 Sep 2020 15:10:37 EDT news520265410 The coronavirus pandemic has highlighted the numerous weaknesses in the U.S. healthcare system. Millions have lost their health insurance and millions more can barely afford it. Racial, ethnic, economic, and geographic disparities in health are widening as death rates from COVID-19 rise. And the financial solvency of hospitals and physician practices is at risk. At some point soon, health care reform will be high on the political agenda. https://medicalxpress.com/news/2020-08-team-solution-healthcare.html Health Wed, 05 Aug 2020 16:00:01 EDT news515851061 The COVID-19 pandemic has led to severe financial stress for both hospitals and physician practices, raising serious concerns that many may either close or be purchased by larger organizations. Such consolidation is well-recognized to lead to higher prices. Whether it will lead to better quality of care is less clear. https://medicalxpress.com/news/2020-08-greater-financial-healthcare-quality.html Health Mon, 03 Aug 2020 16:00:01 EDT news515669238 Even with effective anti-retroviral therapy, patients infected with the Human Immunodeficiency Virus (HIV) sustain central nervous system damage. Whether these problems can be mainly attributed to the disease, its treatments, or the body's immune responses is still being debated, but detecting these changes early and reliably is difficult. https://medicalxpress.com/news/2020-06-reveal-hiv-effects-brain.html HIV & AIDS Tue, 30 Jun 2020 04:08:04 EDT news512708880 As communities across the U.S. have struggled to cope with the effects of the COVID-19 pandemic, many have focused on the lack of widespread testing as a major barrier to safely reopening the country. As progress has been made on this front, concern has shifted to testing accuracy, predominantly with antibody tests, which are designed to identify prior infection. https://medicalxpress.com/news/2020-06-implications-false-negative-covid-.html Diseases, Conditions, Syndromes Fri, 05 Jun 2020 13:47:30 EDT news510583642 There is a strong link between the amount of fast food that pre-school age children consume and their likelihood of becoming overweight or obese, according to a new Dartmouth-led study, published in the journal Pediatric Obesity. https://medicalxpress.com/news/2020-02-fast-food-intake-weight-gain.html Overweight & Obesity Fri, 14 Feb 2020 13:40:10 EST news500909967