https://phys.org/ en-us Latest news from St. Joseph's Hospital and Medical Center Eye-opening research by neurosurgeons from Barrow Neurological Institute and Montreal Neurological Institute has produced the foremost investigation of the origin and evolution of perhaps the most famous concept devised in neurobiology—the homunculus of neurosurgeon Wilder Penfield. The paper, along with a perspective piece, was published in the August issue of World Neurosurgery. The research was conducted by Drs. Mark Preul and Gurpreet Gandhoke at Barrow and Richard Leblanc at Montreal. https://medicalxpress.com/news/2019-12-evolution-famous-concept-brain.html Neuroscience Mon, 09 Dec 2019 10:21:36 EST news495109293 Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontaltemporal dementia (FTD) was published in the April issue of Acta Neuropathologica. The research was conducted by Dr. Rita Sattler and her graduate student Stephen Moore in her laboratory at the Department of Neurobiology at Barrow Neurological Institute, which is dedicated to understanding the mechanisms of disease in ALS, FTD and related neurodegenerative diseases. https://medicalxpress.com/news/2019-04-critical-rna-aberrations.html Neuroscience Fri, 19 Apr 2019 11:04:40 EDT news474890661 Combating glioblastoma remains a major challenge due the complex nature of these tumors, the inability of drugs to penetrate the brain tissue, and lack of correlation between animal models and the human condition. https://medicalxpress.com/news/2018-09-deploy-clinical-trial-regimen-glioblastoma.html Oncology & Cancer Fri, 21 Sep 2018 13:47:15 EDT news456756418 Important research by Barrow Neurological Institute neurosurgeons and University of Washington (UW) scientists on novel imaging technology for malignant brain tumors was published in the August issue of the Nature journal, Scientific Reports. The research was conducted by Drs. Mark Preul and Evgenii Belykh at the Barrow Neurological Institute Neurosurgery Research Laboratory along with Drs. Leonard Nelson and Eric Seibel from the Department of Mechanical Engineering and the Human Photonics Laboratory at the University of Washington. https://medicalxpress.com/news/2018-09-brain-malignant-tumor.html Oncology & Cancer Tue, 04 Sep 2018 10:00:33 EDT news455274024 Research by Barrow Neurological Institute physicians and University of Washington scientists on novel imaging technology for malignant brain tumors was published in the April issue of World Neurosurgery. The research was conducted by Drs. Evgenii Belykh and Mark Preul at the Barrow Neurological Institute Neurosurgery Research Laboratory with technology developed by Drs. Eric Seibel and Leonard Nelson from the Department of Mechanical Engineering and the Human Photonics Laboratory at the University of Washington. https://medicalxpress.com/news/2018-05-brain-gliomas.html Oncology & Cancer Wed, 09 May 2018 16:01:59 EDT news445100508 Barrow Neurological Institute researchers have completed additional experiments that validate the identification of five new genes linked to Amyotrophic Lateral Sclerosis (ALS) - also known as Lou Gehrig's disease. The new study results, validated through five different methods, were published in a full length manuscript in Acta Neuropathologica, validating earlier findings in the project. https://medicalxpress.com/news/2017-12-validate-genes-responsible-amyotrophic-lateral.html Genetics Fri, 01 Dec 2017 11:23:04 EST news431349760 Research by a Barrow Neurological Institute neurosurgery team on novel imaging technique assessment of patients with lumbar spine degeneration was published in the Aug. 28 issue of PLOS ONE. https://medicalxpress.com/news/2017-10-imaging-spinal-degeneration.html Surgery Fri, 20 Oct 2017 10:20:31 EDT news427713620 Research by Jue Wang, MD, at the University of Arizona Cancer Center at Dignity Health St. Joseph's Hospital and Medical Center on "Delay in Diagnosis of Testicular Cancer in a Patient with Down Syndrome" was published in the October issue of Journal of Cancer and Therapeutic Science. https://medicalxpress.com/news/2017-10-successful-treatment-advanced-stage-testicular.html Oncology & Cancer Fri, 13 Oct 2017 15:28:27 EDT news427127297 Research led by the head of the Barrow Neurological Institute and published in the July 20, 2017 issue of The New England Journal of Medicine reveals that subarachnoid hemorrhages, which are caused by ruptured brain aneurysms, account for 5-10 percent of all strokes and are best managed by experienced and dedicated experts at high-volume centers with neurosurgeons, endovascular surgeons and stroke neurologists. The article was co-authored by Barrow President and CEO Michael T. Lawton, M.D. and G. Edward Vates, M.D., Ph.D, of the University of Rochester Medical Center's Department of Neurosurgery."Subarachnoid hemorrhage victims tend to be younger than typical stroke victims, and they risk a greater loss of productive life," Dr. Lawton said. "It is critical that they receive the best treatment for aneurysms - like the multidisciplinary team approach and state-of-the-art therapy like that offered at Barrow." https://medicalxpress.com/news/2017-08-subarachnoid-hemorrhage-expert-treatment.html Surgery Thu, 17 Aug 2017 03:10:38 EDT news422158228 Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research. The research was led by assistant professors at Norton Thoracic Institute, Timothy Whitsett, PhD, and Landon Inge, PhD. https://medicalxpress.com/news/2017-08-strategy-aggressive-lung-cancer.html Oncology & Cancer Wed, 16 Aug 2017 15:53:20 EDT news422117587 Research by scientists at Dignity Health St. Joseph's Hospital and Medical Center's Norton Thoracic Institute was published in the July 12, 2017 issue of Science Translational Medicine titled "Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection." https://medicalxpress.com/news/2017-07-indicator-lung-transplant.html Surgery Thu, 13 Jul 2017 09:40:21 EDT news419157611 Barrow Neurological Institute and IBM Watson Health today announced results of a revolutionary study that has identified new genes linked to Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. The discovery gives ALS researchers new insights that will pave the way for the development of new drug targets and therapies to combat one of the world's most devastating and deadly diseases. https://medicalxpress.com/news/2016-12-team-genes-responsible-als-imb.html Genetics Wed, 14 Dec 2016 17:39:39 EST news400959567 Physicians and researchers at Barrow Neurological Institute have identified a link between domestic violence and traumatic brain injury. The findings could have important implications in the treatment of domestic violence survivors, both in medical and social service communities. The research, led by Dr. Glynnis Zieman, was published in the July issue of Journal of Neurotrauma. https://medicalxpress.com/news/2016-10-barrow-tbi-concussions.html Neuroscience Tue, 11 Oct 2016 15:29:08 EDT news395418539 Researchers at Barrow Neurological Institute have traced the roots of humane medical practices to a pioneering French physician who treated people with deformities as humans instead of "monsters," as they were commonly called. https://medicalxpress.com/news/2016-08-roots-modern-humane-treatment.html Neuroscience Thu, 25 Aug 2016 15:30:50 EDT news391357789 Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for imaging brain tumors in the operating room—a finding that could have important implications for identifying and locating invading cells at the edge of a brain tumor. The research, led by neurosurgeons, Drs. Mark Preul, Nikolay Martirosyan, Peter Nakaji, and Jennifer Eschbacher, was published in the April issue of Neurosurgical Focus. https://medicalxpress.com/news/2016-05-barrow-imaging-tool-surgeon.html Surgery Wed, 04 May 2016 11:52:54 EDT news381581565 Research led by a Dignity Health St. Joseph's Hospital and Medical Center physician on ovarian cancer was published in the Feb. 24, 2016 issue of New England Journal of Medicine. The research was directed by Bradley J. Monk, M.D. and researchers at 12 other medical facilities around the nation. https://medicalxpress.com/news/2016-02-reveals-standard-treatment-ovarian-cancer.html Oncology & Cancer Fri, 26 Feb 2016 16:13:07 EST news375725578 Neurosurgeons at Barrow Neurological Institute in Phoenix are involved with testing the viability of deep brain stimulation (DBS) to treat Alzheimer's disease, a disorder that currently has few treatment options. Results from the Phase 2 study, reported in the Journal of Neurosurgery on Dec. 18, 2015, demonstrated the safety of DBS in Alzheimer's patients. https://medicalxpress.com/news/2016-02-barrow-neurosurgeon-pave-deep-brain.html Neuroscience Fri, 26 Feb 2016 09:20:02 EST news375699800 Researchers at Barrow Neurological Institute have spent years of medical sleuthing across three continents to uncover a brain surgery that changed history. https://medicalxpress.com/news/2015-07-barrow-scientists-rewrite-history-brain.html Neuroscience Wed, 29 Jul 2015 09:24:07 EDT news357380639 Brain tumor experts at Barrow Neurological Institute at Dignity Health St. Joseph's Hospital and Medical Center have launched a revolutionary fast-track approach to cancer research, giving new hope to brain cancer patients. In partnership with The Ben & Catherine Ivy Foundation, the Translational Genomics Research Institute (TGen) and the Barbara Ann Karmanos Cancer Institute, the Barrow studies are the first of their kind. https://medicalxpress.com/news/2015-03-brain-tumor-patients-fast-track.html Oncology & Cancer Tue, 10 Mar 2015 15:59:49 EDT news345221982 Doctors at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix reported today in Lancet Oncology that a new treatment for ovarian cancer can improve response rates (increase the rate of tumor shrinkage) and prolong the time until cancers recur. In addition, this breakthrough showed a trend in improving survival although these data are not yet mature. https://medicalxpress.com/news/2014-06-ovarian-cancer-treatment.html Oncology & Cancer Thu, 19 Jun 2014 18:30:01 EDT news322408784 Research on a deadly form of brain cancer co-authored by a physician at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has been published in the New England Journal of Medicine. The three-year research project led locally by David Brachman, M.D., revealed that a 'promising' drug therapy failed to improve survival among patients with newly diagnosed glioblastoma. https://medicalxpress.com/news/2014-02-bni-reveal-unexpected.html Oncology & Cancer Fri, 28 Feb 2014 12:54:37 EST news312814458 Research on cervical cancer performed by a physician at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center has been published in the New England Journal of Medicine. The multi-site research project by Bradley J. Monk, MD, is expected to change the standard of care for women with advanced cervical cancer. https://medicalxpress.com/news/2014-02-cervical-cancer.html Oncology & Cancer Fri, 21 Feb 2014 14:31:17 EST news312215466 Brain researchers at Barrow Neurological Institute have discovered that we explore the world with our eyes in a different way than previously thought. Their results advance our understanding of how healthy observers and neurological patients interact and glean critical information from the world around them. https://medicalxpress.com/news/2013-04-vision-explore-world.html Neuroscience Fri, 05 Apr 2013 09:08:33 EDT news284371704 Researchers at The University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix have discovered that many women with low-grade serous carcinoma of the ovary or peritoneum have seen their tumors stabilize or shrink after taking a regular dose of the compound selumetinib. https://medicalxpress.com/news/2013-02-breakthrough-ovarian-cancer.html Oncology & Cancer Thu, 14 Feb 2013 16:38:23 EST news280082288 A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, "The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma," was published in PLOS ONE. https://medicalxpress.com/news/2012-12-unique-combination-diet-therapy-successfully.html Oncology & Cancer Tue, 04 Dec 2012 09:37:52 EST news273836259 Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options. https://medicalxpress.com/news/2012-11-gene-involved-lung-tumor-growth.html Oncology & Cancer Thu, 29 Nov 2012 16:43:03 EST news273429766 Vision researchers at Barrow Neurological Institute have made a groundbreaking discovery into the optimization of light sources to human vision. By tuning lighting devices to work more efficiently with the human brain the researchers believe billions of dollars in energy costs could be saved. https://medicalxpress.com/news/2012-11-discovery-ways-optimize-sources-vision.html Neuroscience Thu, 15 Nov 2012 16:00:02 EST news272216037 In what could be a breakthrough in the treatment of deadly brain tumors, a team of researchers from Barrow Neurological Institute and Arizona State University has discovered that the immune system reacts differently to different types of brain tissue, shedding light on why cancerous brain tumors are so difficult to treat. https://medicalxpress.com/news/2012-09-breakthrough-immune-brain-tumors.html Oncology & Cancer Thu, 27 Sep 2012 09:25:28 EDT news267956684 Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center have unveiled how and why the public perceives some magic tricks in recent studies that could have real-world implications in military tactics, marketing and sports. https://medicalxpress.com/news/2012-05-barrow-magic-discoveries.html Neuroscience Tue, 22 May 2012 17:40:00 EDT news256927192 Barrow Neurological Institute researchers Jorge Otero-Millan, Stephen Macknik, and Susana Martinez-Conde share the recent cover of the Journal of Neuroscience in a compelling study into why illusions trick our brains. Barrow is part of St. Joseph's Hospital and Medical Center in Phoenix. https://medicalxpress.com/news/2012-05-barrow-unravel-illusion.html Neuroscience Tue, 01 May 2012 10:52:12 EDT news255086273