https://phys.org/ en-us Latest news from Institute of Cancer Research A gene that is typically active only in reproductive cells may hold the key to new treatments for triple negative breast cancer, according to new research published in the journal Nature Communications. Scientists from the Breast Cancer Now Toby Robins Research Center at The Institute of Cancer Research, London (ICR) and the Breast Cancer Now Research Unit at King's College London, have uncovered a new weakness in triple negative breast cancer linked to a gene called HORMAD1 and a way to target it. https://medicalxpress.com/news/2026-03-triple-negative-breast-cancer-hormad1.html Fri, 13 Mar 2026 13:00:04 EDT news692619781 A study carried out by a team of researchers from The Institute of Cancer Research, London, found that combining two types of genetic tests gives doctors a much better chance of identifying multiple myeloma patients who are at risk of early relapse. https://medicalxpress.com/news/2025-10-accurate-blood-cancer-patients-relapse.html Oncology & Cancer Wed, 15 Oct 2025 10:30:04 EDT news679742754 Scientists have discovered clues that may explain why some treatments stop working for people with bowel cancer—causing about 16,800 deaths in the U.K. every year. https://medicalxpress.com/news/2025-06-scientists-uncover-clues-drug-resistance.html Oncology & Cancer Tue, 17 Jun 2025 07:32:05 EDT news669364322 Scientists have developed a revolutionary AI "fingerprint" technology that can accurately show how cancer cells respond to new drugs, by simply observing changes to their shape. https://medicalxpress.com/news/2025-03-ai-fingerprint-technology-cancer-drugs.html Oncology & Cancer Mon, 24 Mar 2025 11:41:32 EDT news662035284 Prostate cancer that has become resistant to hormone therapy could be treated using a new drug that is currently in clinical trials for ovarian and bile duct cancer, according to research published in the journal Clinical Cancer Research. https://medicalxpress.com/news/2025-01-drug-prostate-cancer-patients-clinical.html Medications Fri, 10 Jan 2025 11:18:18 EST news655730291 Scientists have developed a machine learning tool that can predict how an aggressive type of breast cancer will respond to treatment, and when it will return. https://medicalxpress.com/news/2024-12-aggressive-breast-cancer-paves-treatments.html Oncology & Cancer Mon, 09 Dec 2024 13:09:44 EST news652972180 Researchers have carried out an in-depth analysis of 10,478 cancer genomes across 35 different cancer types, identifying 330 potential cancer-driving genes, 74 of which are newly associated with cancer. The findings highlight the potential to develop new, more targeted treatment options for cancer patients. https://medicalxpress.com/news/2024-11-potential-cancer-genes-paths-precision.html Oncology & Cancer Tue, 19 Nov 2024 12:22:05 EST news651241321 Mobile testing "Man Van" can diagnose prostate cancer in at-risk groups earlier and more affordably than GPs, according to new research. https://medicalxpress.com/news/2024-11-mobile-van-prostate-cancer-quickly.html Oncology & Cancer Mon, 18 Nov 2024 13:20:01 EST news651155636 Researchers have identified a key weakness in acute myeloid leukemia, offering a promising new strategy to delay the progression of this aggressive blood cancer. The discovery focuses on disrupting the function of a certain protein complex that cancer cells, including leukemia cells, rely on to maintain their abnormal growth. https://medicalxpress.com/news/2024-11-treatment-aggressive-leukemia-disrupting-genome.html Oncology & Cancer Tue, 12 Nov 2024 11:03:07 EST news650631779 A powerful, three-drug therapy for aggressive advanced breast cancer doubles the length of time before the cancer progresses, compared with a drug combination currently available on the NHS, new research has shown. https://medicalxpress.com/news/2024-10-powerful-therapy-free-survival-advanced.html Medications Thu, 31 Oct 2024 11:25:27 EDT news649592716 A team from The Institute of Cancer Research, London, has developed a new immuno-PET imaging technique that could spot which glioblastoma patients would respond well to immunotherapy and that tracks the response over time. https://medicalxpress.com/news/2024-10-imaging-technique-glioblastoma-patients-benefit.html Oncology & Cancer Tue, 29 Oct 2024 13:23:05 EDT news649426981 A combination of two drugs that can block the growth of cancer cells has shown promising results in women with a form of ovarian cancer that rarely responds to chemotherapy or hormone therapy. https://medicalxpress.com/news/2024-10-drug-combination-women-rare-treatment.html Oncology & Cancer Mon, 21 Oct 2024 13:33:24 EDT news648736399 A new database of all patients with Lynch syndrome aims to improve treatment and prevention for those at high-risk of cancer. https://medicalxpress.com/news/2024-10-lynch-syndrome-patient-database-genetic.html Oncology & Cancer Mon, 14 Oct 2024 15:09:04 EDT news648137342 Killing breast cancer cells in a way that trains the immune system to recognize and destroy residual cancer cells could offer longer lasting protection to people with the disease. https://medicalxpress.com/news/2024-10-cancer-cells-longer-people-breast.html Oncology & Cancer Mon, 14 Oct 2024 10:16:01 EDT news648119756 Researchers are a step closer to revolutionizing how doctors use radiotherapy to treat patients with muscle-invasive bladder cancer. https://medicalxpress.com/news/2024-10-personalized-radiotherapy-people-bladder-cancer.html Oncology & Cancer Mon, 07 Oct 2024 13:43:44 EDT news647527419 Scientists have developed a new clinical pathway for testing for the cancer-causing faults in the BRCA gene that could ensure patients get the right treatment and boost the number of people who get tested. https://medicalxpress.com/news/2024-10-genetic-pathways-patients-personalized-brca.html Oncology & Cancer Wed, 02 Oct 2024 16:20:37 EDT news647104833 Researchers have examined thousands of genetically defined traits to identify possible causal relationships for eight common cancers. The team evaluated data from more than 860,000 people to uncover potential factors in causing breast, bowel, endometrial, lung, esophageal, ovarian, prostate and kidney cancers. https://medicalxpress.com/news/2024-09-large-scale-cancer-factors.html Oncology & Cancer Thu, 26 Sep 2024 10:33:28 EDT news646565599 A recent study has answered the long-standing question of why improvements in survival outcomes for young people with cancerous soft tissue tumors have lagged behind those of their pediatric and older adult counterparts. By analyzing the protein profiles of different types of soft tissue tumors, known as sarcomas, researchers have shown that there are distinct biological differences between these age groups. https://medicalxpress.com/news/2024-09-biological-door-outcomes-young-adults.html Oncology & Cancer Mon, 23 Sep 2024 15:11:04 EDT news646323061 Scientists have discovered that a protein linked to prostate cancer is associated with more aggressive disease—it could be a new target for treatment and be used to help predict who will become resistant to hormone therapy. https://medicalxpress.com/news/2024-09-drug-aggressive-prostate-cancer.html Oncology & Cancer Wed, 18 Sep 2024 12:50:01 EDT news645882533 Findings from the SIGNIFIED study, which investigated the benefits of screening patients with Li-Fraumeni syndrome by using whole body MRI scans, were presented on Sunday 15 September at the European Society of Medical Oncology (ESMO 2024) congress. https://medicalxpress.com/news/2024-09-routine-mri-scans-cancers-asymptomatic.html Oncology & Cancer Tue, 17 Sep 2024 14:49:52 EDT news645803390 Ribociclib—a drug already used to treat breast cancer—may help slow the growth of diffuse hemispheric glioma (DHG), new research has found. https://medicalxpress.com/news/2024-08-potential-drug-rare-childhood-brain.html Oncology & Cancer Fri, 30 Aug 2024 11:58:36 EDT news644237911 A pioneering study, has provided the most comprehensive analysis to date of the genetic makeup of colorectal cancer (CRC). https://medicalxpress.com/news/2024-08-reveals-previously-unknown-genetic-colorectal.html Oncology & Cancer Thu, 08 Aug 2024 07:29:58 EDT news642320992 Scientists have discovered that some cancer cells pretend to be "super fit" to fool normal healthy cells into giving them their nutrients, allowing them to expand and spread around the body. https://medicalxpress.com/news/2024-07-cancer-cells-super-outsmart-invade.html Medical research Wed, 24 Jul 2024 12:00:21 EDT news641041218 Combining the principles of evolution with artificial intelligence (AI), scientists have proposed a new way to predict the chance of prostate cancer returning. In a recent study, they harnessed computational methods to capture specific tumor measurements relating to the tumor's ability to change over time. They then showed that these measurements correlate with disease recurrence more than a decade after the initial diagnosis. https://medicalxpress.com/news/2024-07-tool-combines-evolution-ai-prostate.html Oncology & Cancer Fri, 12 Jul 2024 11:00:14 EDT news640000808 Cancer's resistance to chemotherapy could be reversed by targeting lactate—the product that builds up as cancer cells convert nutrients to energy, according to new research published in Nature. https://medicalxpress.com/news/2024-07-epilepsy-drug-chemotherapy-stomach-cancer.html Medications Thu, 04 Jul 2024 11:30:02 EDT news639310861 Scientists have added to the list of inherited genetic mutations known to increase the risk of more aggressive prostate cancer. This information could help with identifying prostate cancer patients who are more likely to experience rapid progression of the disease. https://medicalxpress.com/news/2024-07-term-reveals-genetic-mutations-aggressive.html Oncology & Cancer Mon, 01 Jul 2024 13:00:04 EDT news639057599 A new type of blood test can predict the recurrence of breast cancer in high-risk patients, months or even years before they relapse, research has shown. https://medicalxpress.com/news/2024-06-ultra-sensitive-blood-recurrence-breast.html Oncology & Cancer Mon, 03 Jun 2024 16:06:05 EDT news636649561 Researchers have identified the unique features of an exceptionally rare set of childhood brain tumors—a discovery that could pave the way for more effective treatments. https://medicalxpress.com/news/2024-05-scientists-uncover-treatment-pathway-rare.html Oncology & Cancer Fri, 24 May 2024 12:48:04 EDT news635773681 Radiotherapy can be used alongside hormone treatment, delaying the need for chemotherapy and therefore significantly protecting their quality of life for some patients with advanced prostate cancer, according to researchers from The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London. https://medicalxpress.com/news/2024-05-radiotherapy-hormone-therapy-advanced-prostate.html Oncology & Cancer Thu, 09 May 2024 01:51:13 EDT news634438269 Researchers at The Institute of Cancer Research, London, have increased our understanding of how a cancer drug called a PARP inhibitor stops working in women with breast cancer that has spread. This research could ultimately help predict who's more likely to respond to these drugs, and could lead to more effective ways to treat the disease. https://medicalxpress.com/news/2024-05-parp-inhibitor-resistance-advanced-breast.html Oncology & Cancer Wed, 08 May 2024 16:13:03 EDT news634403581