https://phys.org/biology-news/molecular-computational/ en-us Medical Xpress provides the latest news on molecular and Computational biology Every cell in the body contains essentially the same DNA, yet a brain cell behaves differently from a muscle cell or an immune cell. The difference lies largely in how each cell reads its genetic instructions. https://phys.org/news/2026-08-largest-human-cells-dna-chemical.html Cell & Microbiology Tue, 18 Aug 2026 19:20:01 EDT news706276802 A functional nervous system depends on the cooperation of many kinds of cells. As developing organisms build their nervous systems, their neurons must take on different forms and functions to fulfill their designated roles. That carefully orchestrated process gives rise to thousands of different cell types in the human brain. https://phys.org/news/2026-08-genome-complex-reveals-mechanism-neuron.html Cell & Microbiology Tue, 18 Aug 2026 15:40:06 EDT news706272121 Every time a cell divides, it must accurately copy its entire genetic instruction manual. Before this process can begin, cells load their DNA-copying motor—a complex of six subunits known as the MCM2-7 helicase—onto DNA. However, this motor is deliberately kept inactive to prevent replication from starting at the wrong time. https://phys.org/news/2026-08-snapshots-reveal-key-dna-replication.html Cell & Microbiology Tue, 18 Aug 2026 15:20:04 EDT news706271761 Understanding "who eats whom" is the key to keeping our oceans alive—and our dinner plates full. However, this invisible network that makes up the food chain can unravel with the pull of just one thread. Overfish one species, and its predators starve. Cut off a tiny prey species, and the entire food chain collapses—including us. https://phys.org/news/2026-08-mathematical-tool-uncover-nature.html Ecology Tue, 18 Aug 2026 14:50:01 EDT news706282261 AI optimists will be encouraged by a recent report on the state of the world's plants and fungi by the Royal Botanic Gardens, Kew. https://phys.org/news/2026-08-ai-million-digitized-specimens-reveal.html Ecology Tue, 18 Aug 2026 14:10:01 EDT news706279021 Coronins are found throughout the animal kingdom, from single-celled amoebae to humans, and are involved in many vital processes, including immunity, development and cell survival. For decades, textbooks and hundreds of scientific papers have described coronins primarily as proteins that bind to actin, a key component of the cytoskeleton. https://phys.org/news/2026-08-cells-remodel-actin-coronins-textbook.html Cell & Microbiology Tue, 18 Aug 2026 14:00:10 EDT news706268761 Between 29,000 and 19,000 years ago, the planet experienced some of its coldest temperatures and drastic landscape changes at the peak of the Ice Age, during the Last Glacial Maximum (LGM), the period of most extensive global ice cover. Humans, despite being unaccustomed to such icy temperatures and surroundings, survived through the age. https://phys.org/news/2026-08-ancient-jomon-dna-reveals-hidden.html Evolution Tue, 18 Aug 2026 11:40:10 EDT news706266198 The narwhal's impressive tusk has long been the subject of myths. In the Middle Ages, they were sold as unicorn horns believed to possess magical powers. Now, an international team of researchers led by Aarhus University has solved the mystery of how the tusk acquires its twisted structure. https://phys.org/news/2026-08-spiral-narwhal-tusks-resistance.html Plants & Animals Tue, 18 Aug 2026 11:00:08 EDT news706175641 Researchers at Karolinska Institutet and Stockholm University have developed a new tool that estimates a cell's biological age by analyzing its gene activity. In an article published in the journal Advanced Science, they also demonstrate how the tool can be used to identify substances that influence cellular aging. https://phys.org/news/2026-08-gene-tool-biological-age-cells.html Cell & Microbiology Tue, 18 Aug 2026 09:00:01 EDT news706258189 In humans and many other animals, a mother's age can affect the physical and behavioral characteristics of the next generation. Scientists call these changes maternal age effects, and while they are widespread across the animal kingdom, researchers still don't fully understand how or why they occur. https://phys.org/news/2026-08-molecular-memory-mother-age-echoes.html Plants & Animals Mon, 17 Aug 2026 22:20:02 EDT news706188931 The deoxyribonucleic acid (DNA) of living organisms contains regulatory elements that control when, where and to what extent specific genes are turned on or off. They can be co-opted to create "gene switches" that hold significant potential for understanding gene expression and for therapeutic applications, particularly for the noninvasive treatment or management of genetic disorders. https://phys.org/news/2026-08-molecular-electromagnetic-sensor-enable-remote.html Biotechnology Mon, 17 Aug 2026 19:40:04 EDT news706196881 Histone variants help establish DNA methylation at transposons (jumping genes) while preventing this epigenetic modification from spreading to essential genes in plants, a study from the Institute of Science Tokyo reveals. By revealing how these chromosome-associated proteins guide the formation of precise epigenomic patterns, the findings provide new insights into the selective silencing of transposons, laying the groundwork for future epigenome-editing technologies for crop improvement and disease research. https://phys.org/news/2026-08-silence-genes-essential.html Plants & Animals Mon, 17 Aug 2026 16:40:03 EDT news706189934 Cells travel through the body both individually and in collective groups during development, wound healing and diseases such as cancer. New research from the McKelvey School of Engineering at Washington University in St. Louis shows that cells can sense even the smallest defects, or micro-injuries, in the surface beneath which they travel and stall long enough to begin the healing process. https://phys.org/news/2026-08-tiny-feet-cells-defects-stall.html Cell & Microbiology Mon, 17 Aug 2026 15:20:06 EDT news706187761 The complete genome of the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they? https://phys.org/news/2026-08-tb-gene-reveals-unexpected-biological.html Cell & Microbiology Mon, 17 Aug 2026 15:00:06 EDT news705927228 By the early 1990s, there were only around 20 Florida panthers left on the planet. https://phys.org/news/2026-08-poor-genetic-health-threatens-species.html Plants & Animals Mon, 17 Aug 2026 09:20:02 EDT news706167542 In ant colonies, a single ant can be the catalyst for a wave of mob activity, launching brief bursts of coordinated movement involving hundreds or even thousands of swarming workers, according to new simulations from New Jersey Institute of Technology. https://phys.org/news/2026-08-scientists-simulating-ant-swarms-mover.html Ecology Sat, 15 Aug 2026 07:00:03 EDT news705724257 Researchers at the University of Maryland and their collaborators have cloned a gene that makes wheat resistant to feeding by Hessian fly larvae and demonstrated its direct interaction with a protein produced by the insect. The research breaks through a longstanding barrier to understanding and engineering pest resistance in wheat. It is described in a research paper published Aug. 14, 2026, in the journal Science Advances. https://phys.org/news/2026-08-wheat-gene-hessian-fly-resistance.html Molecular & Computational biology Fri, 14 Aug 2026 18:20:04 EDT news705936181 Epithelial cells are the tiny shields that line and protect our bodies. In a developing embryo, epithelial cells grow, divide and move into positions to form the outer layers of our skin and the surfaces of our organs and blood vessels. When we scrape our skin, suffer an internal tear or undergo surgery, epithelial cells migrate to the site of injury to heal a wound. And when epithelial cells go haywire, they can turn malignant and spread through the body as cancer. https://phys.org/news/2026-08-cells-pulse-malignant-longest.html Cell & Microbiology Fri, 14 Aug 2026 16:40:01 EDT news705932882 A research team led by Director Kim V. Narry at the Center for RNA Research within the Institute for Basic Science (IBS) has discovered compact viral RNA elements that can make mRNA more stable and increase protein production. These elements could provide a simple way to develop longer-lasting and more efficient mRNA technologies for vaccines and other RNA-based therapeutics. https://phys.org/news/2026-08-stable-rna-elements-possibilities-mrna.html Biotechnology Fri, 14 Aug 2026 13:20:04 EDT news705931142 A host that sheds an abundance of parasites might seem like an obvious disease-spreading threat. But new research suggests that shedding large volumes of parasites does not dictate transmission efficiency—and "super-shedders" may not be the superspreaders of infectious disease outbreaks. https://phys.org/news/2026-08-quality-quantity-super-shedders-superspreaders.html Ecology Fri, 14 Aug 2026 12:40:01 EDT news705916929 Scientists often describe life as a series of chemical reactions. Pallav Kosuri, Ph.D., describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells and bodies—without movement, there is no life. https://phys.org/news/2026-08-tiny-dna-rotor-microscopes-track.html Biotechnology Fri, 14 Aug 2026 10:40:02 EDT news705921781 Being an elite athlete—at least for a mouse—does not shorten lifespan or limit how many children one can have. This is the finding of a study 30 years in the making, and it runs counter to accepted evolutionary theory. https://phys.org/news/2026-08-mouse-assumed-offs-athleticism-fertility.html Ecology Thu, 13 Aug 2026 08:40:02 EDT news705825983 Designing an effective antibody drug is like searching for the right key in a warehouse of locks. Scientists may begin with millions—or even billions—of antibody candidates, but only a tiny fraction will recognize and bind tightly to the disease target. Identifying those rare candidates has long been one of the biggest challenges in developing antibody medicines. https://phys.org/news/2026-08-ai-biology-antibodies-drug-discovery.html Biotechnology Thu, 13 Aug 2026 05:00:03 EDT news705763776 Scientists have crossed an important line in biological engineering. In a recent study, researchers used artificial intelligence to design complete sets of genetic instructions for bacteriophages, viruses that infect bacteria. Some of those computer-generated designs produced working viruses when they were built and tested in the laboratory. https://phys.org/news/2026-08-aidesigned-viruses-biosecurity-pace.html Biotechnology Wed, 12 Aug 2026 19:20:07 EDT news705756534 The DNA of Asian elephants tells a concerning story. Although all four subspecies are under pressure, there are considerable differences in their genetic health. In an article published in the journal Genome Biology and Evolution, researchers show how whole-genome analyses can help identify more precisely which populations are most vulnerable and where conservation measures could have the greatest impact. https://phys.org/news/2026-08-dna-highlights-genetic-vulnerability-asian.html Ecology Wed, 12 Aug 2026 16:50:02 EDT news705755261 Researchers from the RIKEN Center for Sustainable Resource Science (CSRS) and RIKEN Pioneering Research Institute (PRI) in Japan, together with collaborators from the University of Münster, Germany, have developed a new hydrogel that offers significant advantages over others currently on the market in the field of biomaterials. https://phys.org/news/2026-08-synthetic-peptide-electrically-polarized-hydrogel.html Biotechnology Wed, 12 Aug 2026 16:00:07 EDT news705755101 The decades-old scientific quest to create brand-new proteins has been turbocharged in the era of artificial intelligence. https://phys.org/news/2026-08-qa-deploying-ai-proteins-nature.html Biotechnology Wed, 12 Aug 2026 13:40:04 EDT news705756123 Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane-embedded proteins. When protein synthesis fails, ribosomes recruit quality control factors to eliminate the resulting defective proteins. https://phys.org/news/2026-08-quality-proteins-cellular-membrane-ribosome.html Cell & Microbiology Wed, 12 Aug 2026 10:20:04 EDT news705746175 Bumblebees are able to learn to associate new odors with their colony's queen, instead of being preprogrammed to recognize the queen's pheromones from birth, according to a new study led by researchers at Penn State. For the study, published in the journal Communications Biology, the researchers treated buff-tailed bumblebee queens daily with one of two different floral scents as they built their colonies. https://phys.org/news/2026-08-bumblebees-associate-queen.html Ecology Wed, 12 Aug 2026 08:40:03 EDT news705742562 Fluorescent protein imaging is an indispensable tool in life science research, enabling visualization of protein movement and localization, gene expression, signaling pathways, protein-protein interactions and more. For simultaneous analysis of multiple proteins (i.e., multiplex imaging), a variety of fluorescent proteins that emit different colors (blue, green, yellow and red) have been developed. https://phys.org/news/2026-08-fluorescence-lifetime-imaging-distinguishes-multiple.html Plants & Animals Tue, 11 Aug 2026 18:40:05 EDT news705679441