High-throughput platform enables activity mapping of emerging cancer drug targets
A powerful new biochemical platform is fueling the study of a family of enzymes that are promising targets for cancer treatment.
A powerful new biochemical platform is fueling the study of a family of enzymes that are promising targets for cancer treatment.
Biochemistry
Nov 28, 2018
0
61
A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and ...
Biochemistry
Sep 24, 2018
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132
For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects ...
Biochemistry
Jun 13, 2018
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24
Ancient microbes that thrive in some of the world's most extreme environments and modern-day humans have more in common than meets the eye—namely, they both respire and conserve energy using a similar molecular mechanism, ...
Biochemistry
May 10, 2018
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23
Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the development of new medications for cancer and a host of other diseases.
Biochemistry
Jan 22, 2018
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27
A team led by scientists at Van Andel Research Institute (VARI) has revealed for the first time the atomic-level structure of a promising drug target for conditions such as stroke and traumatic brain injury.
Biochemistry
Dec 6, 2017
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155
A team spearheaded by Van Andel Research Institute scientists has answered a long-standing question that may lead to more effective drugs with fewer side effects for diseases ranging from heart failure to cancer.
Biochemistry
Jul 27, 2017
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94
An international collaboration of life scientists, including experts at Van Andel Research Institute, has described in exquisite detail the critical first steps of DNA replication, which allows cells to divide and most advanced ...
Cell & Microbiology
Feb 21, 2017
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14
Scientists at Van Andel Research Institute and Rockefeller University have successfully described a crucial structure involved in DNA replication, placing another piece in the puzzle of how life propagates.
Biotechnology
Jan 16, 2017
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497
Just as nations around the globe carefully guard their defense secrets, so do plants.
Biotechnology
Aug 10, 2015
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742