First structure of human cotransporter protein family member solved

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles—ions—across ...

3-D atomic structure of TRPML1 ion channel published

UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the first ...

Researchers use snake venom to solve structure of muscle protein

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening ...

Scientists identify mechanism crucial for COVID-19 virus replication

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication. The finding, published in Nature, ...

Urge to merge: Understanding how cells fuse

Scientists have known for a decade that cells that fuse with others to perform their essential functions—such as muscle cells that join together to make fibers—form long projections that invade the territory of their ...

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