Scientists set out to map the world's genomic diversity

An international consortium of scientists has launched a new effort to create a reference genome that captures the genetic diversity of all the peoples of the world. The researchers describe the initiative, called the Human ...

Signaling proteins shown to play key role in tuberculosis biology

A set of 10 signaling proteins found in the microbe that causes tuberculosis (TB) play a far larger role in regulating the bacterium's growth, development and behavior than previously thought, according to recent research. ...

Reinforcement learning: From board games to protein design

Scientists have successfully applied reinforcement learning to a challenge in molecular biology. The team of researchers developed powerful new protein design software adapted from a strategy proven adept at board games like ...

Cilia-free stem cells offer new path to study rare diseases

A group of rare diseases called "ciliopathies"—polycystic kidney disease notable among them—emerge from defects in cilia, the tiny hair-like structures on the surface of almost every cell type. But the specific molecular-level ...

SpyLigation technology uses light to switch on proteins

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study ...

Deep learning tool identifies bacteria in micrographs

Omnipose, a deep learning software, is helping to solve the challenge of identifying varied and miniscule bacteria in microscopy images. It has gone beyond this initial goal to identify several other types of tiny objects ...

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