At some point during human evolution, a handful of genetic changes triggered a dramatic threefold expansion of the brain's neocortex, the wrinkly outermost layer of brain tissue responsible for everything from language to ...
Evolution
Feb 8, 2019
17
254
Within a few years, Jim Johnsen and Delaney Van Riper may be among the first to benefit from CRISPR-Cas9 gene editing, a breakthrough that has already revolutionized biology research and promises to resurrect gene therapy.
Biotechnology
Oct 26, 2018
2
642
A collaboration between three labs at UC San Francisco has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins (pronounced "INT-uh-grins"). Integrins are associated with ...
Biochemistry
Jul 31, 2018
0
13
UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
Biotechnology
Jul 20, 2018
0
409
In an achievement that has significant implications for research, medicine, and industry, UC San Francisco scientists have genetically reprogrammed the human immune cells known as T cells without using viruses to insert DNA. ...
Biotechnology
Jul 11, 2018
1
665
Recent leaps in gene editing technology have brought ideas that just a decade ago seemed like science fiction to the cusp of reality.
Biotechnology
Jul 6, 2018
0
3
Opioid drugs like morphine and fentanyl are a mainstay of modern pain medicine. But they also cause constipation, are highly addictive, and can lead to fatal respiratory failure if taken at too high a dose. Scientists have ...
Biochemistry
Jun 22, 2018
0
74
A so-called "jumping gene" that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development, according to a new study in mice led ...
Cell & Microbiology
Jun 21, 2018
0
143
In 2014, California voters approved Proposition 47, which reclassified drug possession offenses from felonies or "wobblers"—which prosecutors can charge as either felonies or misdemeanors—to misdemeanors, and in the process ...
Social Sciences
Jun 21, 2018
1
2
How do complex biological structures—an eye, a hand, a brain—emerge from a single fertilized egg? This is the fundamental question of developmental biology, and a mystery still being grappled with by scientists who hope ...
Cell & Microbiology
May 31, 2018
2
412
