Shapeshifting receptors may explain mysterious drug failures

For sugar to taste sweet and for coffee to be stimulating, or even for light to be seen, first they all need to land on a G protein-coupled receptor. Ubiquitous and diverse, these receptors are a cell's chemical detection ...

From the tiny testes of flies, new insight into how genes arise

In the battle of the sexes, males appear to have the innovative edge—from a genetic standpoint, at least. Scientists are finding that the testes are more than mere factories for sperm; these organs also serve as hotspots ...

Learning from experience is all in the timing

As animals explore their environment, they learn to master it. By discovering what sounds tend to precede predatorial attack, for example, or what smells predict dinner, they develop a kind of biological clairvoyance—a ...

Cellular rivalry promotes healthy skin development

Not all cells are destined for greatness. Deemed unfit to serve in the body, some are killed off during early development through a process called cell competition. This phenomenon has previously been documented in flies ...

New microscopy technique peers deep into the brain

In order to understand the brain, scientists must be able to see the brain—cell by cell, and moment by moment. However, because brains comprise billions of microscopic moving parts, faithfully recording their activity comes ...

New tool allows scientists to catch elusive protein in action

Like many of the processes that drive a cell's basic functions, those enabling the splitting of a newly-replicated cell into two, shown above, happen quickly. So quickly, in fact, that scientists often have a hard time pinpointing ...

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