The team of Johannes Zuber at the IMP in Vienna, Austria, managed to overcome remaining key limitations of RNA interference (RNAi) - a unique method to specifically shut off genes. By using an optimized design, the scientists ...
Cell & Microbiology
Dec 13, 2013
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In most animals and plants, the life cycle of an individual begins with fertilization, when egg and sperm fuse to combine their genetic material. Together, they form the zygote, the first cell of an embryo that will eventually ...
Cell & Microbiology
Sep 24, 2021
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45
When one cell divides into two - that is how all forms of life are propagated - the newly born daughter cells have to be equipped with everything they will need in their tiny lives. Most important of all is that they inherit ...
Cell & Microbiology
Aug 12, 2016
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31
Proteins are the essence of life: they give structure to cells and organelles, catalyze metabolic reactions, build, break, tug, and pull—they carry out most of the actions that sustain a cell's existence.
Biotechnology
Jun 9, 2021
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10
Mature egg cells and early embryos do not generate their own RNA molecules—instead, they rely on stored maternal RNAs to synthesize their proteins. As the embryo develops, some of these RNAs become superfluous and need ...
Plants & Animals
Mar 10, 2021
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16
The cohesin molecule ensures the proper distribution of DNA during cell division. Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna can now prove the concept of its carabiner-like function by visualizing ...
Cell & Microbiology
Nov 21, 2014
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Cells never forget to take out the trash. It has long been known that cells tag proteins for degradation by labelling them with ubiquitin, a signal described as "the molecular kiss of death". Tim Clausen's group at the Research ...
Cell & Microbiology
Oct 7, 2016
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6
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins. ...
Cell & Microbiology
Jan 18, 2013
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Twenty years ago, the protein complex cohesin was first described by researchers at the IMP. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped structure of cohesin keeps ...
Biotechnology
Apr 20, 2017
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2
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna uncover basic mechanisms of action for hormones.
Cell & Microbiology
Apr 1, 2014
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