Scientists identify key factor that maintains stem cell identity

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study by NYU Langone Medical Center scientists. The study is published online ...

First functional 'designer' chromosome synthesized in yeast

An international team of scientists led by Jef Boeke, PhD, director of NYU Langone Medical Center's Institute for Systems Genetics, has synthesized the first functional chromosome in yeast, an important step in the emerging ...

Molecular engines star in new model of DNA repair

Our health depends in large part upon the ability of specialized enzymes to find and repair the constant barrage of DNA damage brought on by ultraviolet light radiation and other sources. In a new study NYU School of Medicine ...

Researchers discover new way to form extracellular vesicles

Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals ...

Scientists crack sparse genome of microbe linked to autoimmunity

Scientists have deciphered the genome of a bacterium implicated as a key player in regulating the immune system of mice. The genomic analysis provides the first glimpse of its unusually sparse genetic blueprint and offers ...

Eradicating dangerous bacteria may cause permanent harm

In the zeal to eliminate dangerous bacteria, it is possible that we are also permanently killing off beneficial bacteria as well, posits Martin Blaser, MD, Frederick H. King Professor of Medicine, professor of Microbiology ...

Researchers reveal a new mechanism of genomic instability

Researchers at NYU School of Medicine have discovered the cellular mechanisms that normally generate chromosomal breaks in bacteria such as E. coli. The study's findings are published in the August 18 issue of the journal ...

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