Engineered E. coli delivers therapeutic nanobodies to the gut
Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.
Massachusetts General Hospital, (Mass General) was established in 1811 in Boson, Massachusetts. Mass Geneeral is the teaching hospital for Harvard. MGH is part of the large medical science research and patient care complex that is consistently rated in the top 10 of teaching hospitals in the USA. MGH is noted for its work in endocrinology, cancer, digestive disorders, neurosurgery, and recently made signiificant break through in organ transplant rejection research.
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Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.
Cell & Microbiology
Mar 31, 2023
0
85
TDP-43 is an RNA-binding protein that normally resides in the nucleus of neurons but is abnormally located in the cytoplasm of neurons in most patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, ...
Cell & Microbiology
Mar 20, 2023
0
3
While each person gets dressed at least 29,000 times in the course of their lives, empirical science has paid little attention to why we select the everyday clothes that help mold our image.
Social Sciences
Feb 1, 2023
0
7
Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly.
Biotechnology
Jan 17, 2023
0
173
Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs, including the heart, lungs, liver, stomach, and ...
Molecular & Computational biology
Jan 5, 2023
3
91
Oxygen is vital for life, and clinicians can provide supplemental oxygen to patients through face masks and nasal tubes, but there are no methods available for delivering oxygen directly into cells.
Cell & Microbiology
Oct 12, 2022
0
27
A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, which is published in Nature ...
Biotechnology
Oct 11, 2022
0
60
Although chemotherapy can be a lifesaving treatment for patients with cancer, some of these medications can damage the heart. A team led by researchers at Massachusetts General Hospital (MGH) recently developed a nanoparticle ...
Bio & Medicine
Aug 15, 2022
0
361
Researchers led by Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found that lifetime depression, trauma of having a loved one murdered, and post-traumatic stress disorder (PTSD) are the three ...
Social Sciences
May 4, 2022
0
31
The body's ability to respond to various types of stress is essential for maintaining health, and failure of such adaptive stress responses can trigger or worsen numerous diseases. New research led by investigators at Massachusetts ...
Cell & Microbiology
Apr 5, 2022
0
386