The Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada was established in 1985 by an endowment from the Lunenfeld and Kunin families. It comprises 36 principal investigators, has a budget of C$90 million (2005/6), has over 200 trainees and approximately 600 staff. The Institute conducts research into various forms of cancer (colon, breast, pancreatic, prostate), neurological disorders and brain illnesses, women's and infants' health, diabetes, developmental biology, stem cell biology and tissue regeneration, mouse models of human disease, genomic medicine and systems biology. The Institute has 100,000 sq ft (9,300 m) of space and is split between the main hospital and the Joseph and Wolf Lebovic Health Complex. The founding director was Dr. Louis Siminovitch (1984–1994), followed by Dr. Alan Bernstein (1995–2000), Drs. Janet Rossant and Anthony Pawson (2001–2002), Dr. Anthony Pawson (2002–2005) and Dr. James Woodgett (2005-).
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Researchers at Sinai Health have used a tiny worm to track how an animal's brain changes throughout its lifetime, shedding new light on how human brains develop.
Molecular & Computational biology
Aug 4, 2021
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Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens ...
Cell & Microbiology
Jun 2, 2021
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A team of researchers at Sinai Health System's Lunenfeld-Tanenbaum Research Institute (LTRI) and University of Toronto's Donnelly Centre has developed a new technology that can stitch together DNA barcodes inside a cell ...
Biotechnology
Apr 22, 2016
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Researchers led by Dr. Helen McNeill at the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, which ...
Cell & Microbiology
Sep 11, 2014
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A possible therapeutic target for control of blood glucose in the treatment of type 2 diabetes and obesity has been identified by Dr. Anita Johswich and her colleagues. Their findings were published in Journal of Biological ...
Biochemistry
Apr 30, 2014
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Baker's yeast is giving scientists a better understanding of drug interactions, which are a major cause of hospitalization and illness world-wide.
Biochemistry
Apr 24, 2014
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