In 2008 the Spanish company PharmaMar, dedicated to developing marine-derived drugs against cancer, isolated a promising substance called pipecolidepsin A from the sponge Homophymia lamellosa collected off the coast of Madagascar. ...
Biochemistry
Sep 4, 2013
0
1
Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate ...
Cell & Microbiology
Jun 1, 2021
0
201
The genetic material—DNA—of plants and animals (within the latter humans) is stored inside the cell, and DNA packing is guaranteed by proteins called histones. Furthermore, histones play a key role in regulating the activation ...
Molecular & Computational biology
Apr 17, 2020
0
12
Scientists headed by Ferran Azorín at the Institute for Research in Biomedicine (IRB Barcelona) have discovered why histone 1 is a major protection factor against genomic instability and a vital protein. Their study of the ...
Cell & Microbiology
Aug 18, 2017
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41
Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...
Molecular & Computational biology
Nov 1, 2021
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54
A study by IRB Barcelona's Development and Growth Control Laboratory, headed by ICREA researcher Marco Milán, reveals how Dpp and Wg morphogens regulate organ proportions and patterning of the fly wing through independent ...
Cell & Microbiology
Feb 21, 2020
0
12
Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs. Adverse effects are one of the main causes of hospital ...
Biochemistry
Apr 19, 2013
0
0
Knowledge of the minute details of the proteins that are linked to diseases is crucial if we are to discover therapeutic targets and thus pave the way for possible treatments. Such knowledge gains even more relevance when ...
Biochemistry
Jun 10, 2016
0
14
Researchers at the Institute for Research in Biomedicine (IRB Barcelona), Cambridge University and New York University, led by Modesto Orozco, Group Leader at IRB Barcelona, Director of Life Sciences at the Barcelona Supercomputing ...
Biochemistry
Jul 28, 2015
0
24
Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles ...
Cell & Microbiology
Jan 16, 2018
0
29
