BigH1—the key histone for male fertility

Researchers in the Chromatin Structure and Function Lab at the Institute for Research in Biomedicine (IRB Barcelona) have identified the histone BigH1 as a key protein in stem cell differentiation to male sex cells. Histones ...

Histone 1, the guardian of genome stability

Scientists headed by Ferran Azorín at the Institute for Research in Biomedicine (IRB Barcelona) have discovered why histone 1 is a major protection factor against genomic instability and a vital protein. Their study of the ...

Drosophilia brings to light the role of morphogens in limb growth

Researchers working in the Development and Growth Control Lab at IRB Barcelona reveal that the Dpp gene (BMP in humans) plays a double role in the structural organisation and growth of the wings of the fruit fly Drosophila ...

First 3-D observation of nanomachines working inside cells

Currently, biologists who study the function of protein nanomachines isolate these complexes outside the cell in test tubes, and then apply in vitro techniques that allow them to observe their structure down to the atomic ...

New signal involved in limb growth found in flies

Many of the secrets of life, such as terminal size and shape, have been uncovered in studies performed over a century involving animal models such as the fruit fly Drosophila melanogaster. Now, IRB Barcelona researchers headed ...

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