The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.
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FMI researchers developed an imaging approach that allowed them to visualize individual molecules involved in the cell's response to stress.
Cell & Microbiology
Jun 29, 2022
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16
Even small differences in how fast animals grow during development can sum up to large differences in their adult body size. Nevertheless, adults of the same species are usually nearly identical in size. Benjamin Towbin, ...
Plants & Animals
Jun 07, 2022
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44
FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.
Cell & Microbiology
May 11, 2022
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117
Cilia, the little "hairs" attached to almost all cells of the human body, play a role in various cellular functions and cause diseases called ciliopathies when they are defective. Researchers from the group of Patrick Matthias ...
Molecular & Computational biology
Apr 20, 2022
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55
Our actions are motivated by the goals we want to achieve. However, little is known about the mechanism in our brains that allow us to make the right decisions to reach our goals. Researchers in the Lüthi lab now identified ...
Plants & Animals
Jan 07, 2022
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263
Hydras are tiny creatures with regenerative superpowers: they can renew their stem cells and replace damaged body parts in only a few days. Now, researchers in the Tsiairis group have found that mechanical forces turn on ...
Cell & Microbiology
Dec 13, 2021
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15
Chemical modifications of histones, the small proteins around which DNA is wrapped, are known to affect gene expression. In a study conducted in C. elegans, researchers from the Gasser group show that the defining modification ...
Cell & Microbiology
Nov 15, 2021
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53
Researchers in the Friedrich group have contributed to create an atlas that links subcellular structures to gene expression in each cell of the sea worm Platynereis dumerilii, a key model organism for the study of development ...
Evolution
Oct 05, 2021
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12
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 08, 2021
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30
How can proteins bind DNA in the cell nucleus, where it is present in form of chromatin, tightly wrapped around histones and therefore mostly inaccessible? Recently, several studies began to uncover the various strategies ...
Cell & Microbiology
Jun 29, 2021
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