Molecular compass for cell orientation

Molecular compass for cell orientation
When the scientists removed one part of the receptor -- CANAR, the plant's veins were formed seemingly randomly (right side). The left side shows the normal vein formation. Credit: Jakub Hajný / IST Austria

Plants have veins that transport nutrients throughout their whole body. These veins are organized in a highly ordered manner. The plant hormone auxin travels directionally from cell-to-cell and provides cells with positional information, coordinating them during vein formation and regeneration. Until now, it remained a mystery how cells translate auxin signals into a formation of a complex system of veins. Scientists at the Institute of Science and Technology (IST) Austria discovered a molecular machinery that perceives a local auxin concentration and allows cells to synchronize their behavior to coordinate veins formation and regeneration. The scientists published their study in the journal Science. This phenomenon also applies to wound healing and might lead to more mechanically resistant plants and further agricultural implications.

The human body uses veins and blood to transport nutrients and oxygen throughout the body. Plants use a similar approach, the vascular systems. These veins transport nutrients for survival and define the size, structure, and position of new leaves and allow long-range communication between distant organs. Now, scientists from the group of Prof Jiri Friml at IST Austria, discovered how the dictates the newly formed veins' position. "Auxin decides which will differentiate into vascular tissue and orchestrates them to form intricate vein patterns," explains Jakub Hajný, who led the study. When cells have no ability to sense auxin signal, plant forms disorganized veins with disconnections that limit nutrients distribution. In case of mechanical damage, it also decreases regeneration after wounding.

Cell orientation in a tissue

Already decades ago, scientists suspected that auxin is the vein-inducing signal organizing tissue into the formation of conserved vein patterns. However, scientists could not understand how the cells decrypt this chemical signal into a cellular response so far. The Friml group managed to identify the responsible proteins, called CAMEL and CANAR which serves as auxin sensor. The CAMEL/CANAR complex most likely perceives the auxin concentration in the neighborhood and allows cells to synchronize their orientations to create continuous . "It is basically a molecular compass for cell orientation, only instead of a , it detects auxin concentration," explains Jakub Hajný. Thus, the team discovered underlying auxin-mediated vein formation and regeneration.

Molecular compass for cell orientation
The left picture shows how a plant usually regenerates a wound. The right side depicts the regeneration without the CAMEL/CANAR receptor complex. The injury cannot regenerate properly. Credit: Jakub Hajný / IST Austria

Explore further

Study sheds new light on vein formation in plants

More information: Receptor kinase module targets PIN-dependent auxin transport during canalization. Science (2020). … 1126/science.aba3178
Journal information: Science

Citation: Molecular compass for cell orientation (2020, October 29) retrieved 7 December 2021 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors