Researchers provide detailed genetic information on fish commonly used in environmental toxicology studies

The fathead minnow (Pimephales promelas) has long been a premier animal model for research and regulation related to environmental toxins. Unfortunately, however, genetic information about this species is incomplete. The lack of genome sequence information for the species has limited scientists' ability to dissect complex traits, evaluate genetic markers, identify gene regulatory sequences, and elucidate biological pathways.

Now investigators have addressed the need for genome-scale information for the fathead minnow by generating in-depth sequence information using next generation sequencing methods and making both the and two draft genome assemblies publicly available.

The information will enhance the utility of the fathead minnow as a model organism for studying the mechanisms of . "This research will help build the scientific foundation for greater use of predictive ecotoxicology and illustrates the collaborative synergy among industry, academia, and regulatory agency researchers," said Dr. Robert Hoke, lead author of the Environmental Toxicology & Chemistry study.


Explore further

Scientists sequence genomes of microscopic worms beneficial to agriculture

More information: Frank R. Burns et al. Sequencing and de novo draft assemblies of a fathead minnow ( ) reference genome , Environmental Toxicology and Chemistry (2015). DOI: 10.1002/etc.3186
Provided by Wiley
Citation: Researchers provide detailed genetic information on fish commonly used in environmental toxicology studies (2015, November 4) retrieved 16 September 2019 from https://phys.org/news/2015-11-genetic-fish-commonly-environmental-toxicology.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
20 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more