Coating nanotubes with aluminum oxide lowers risk of lung injury

October 3, 2014 by Matt Shipman, North Carolina State University
Coating nanotubes with aluminum oxide lowers risk of lung injury
Image of a multi-walled carbon nanotube. Image credit: Eric Wieser, via WikiMedia Commons.

(Phys.org) —A new study from North Carolina State University and the National Institute of Environmental Health Sciences (NIEHS) finds that coating multiwalled carbon nanotubes (CNTs) with aluminum oxide reduces the risk of lung scarring, or pulmonary fibrosis, in mice.

"This could be an important finding in the larger field of work that aims to predict and prevent future diseases associated with engineered nanomaterials," says James Bonner, a professor of environmental and molecular toxicology at NC State and senior author of a paper describing the work. "Our goal is to find ways to make sure that carbon nanotubes don't become the next asbestos."

Multiwalled CNTs have a wide array of applications, ranging from sporting goods to electronic devices. And while these materials have not been associated with adverse health effects in humans, research has found that multi-walled CNTs can cause pulmonary fibrosis and lung inflammation in animal models.

"Because multiwalled CNTs are increasingly used in a wide variety of products, it seems likely that humans will be exposed to them at some point," Bonner says. "That means it's important for us to understand these materials and the potential risk they pose to human health. The more we know, the better we'll be able to engineer safer materials."

For this study, the researchers used atomic layer deposition to coat multiwalled CNTs with a thin film of and exposed mice to a single dose of the CNTs, via inhalation.

The researchers found that CNTs coated with aluminum oxide were significantly less likely to cause in mice. However, the coating of aluminum oxide did not prevent .

"The aluminum oxide coating doesn't eliminate health risks related to multi-walled CNTs," Bonner says, "but it does lower them."

Explore further: Carbon nanotubes found to be toxic to aquatic animals

More information: Taylor AJ, McClure CD, Shipkowski KA, Thompson EA, Hussain S, et al. (2014) Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo. PLoS ONE 9(9): e106870. DOI: 10.1371/journal.pone.0106870

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gkam
1 / 5 (1) Oct 03, 2014
Good. One aspect of graphite not told to the public is the effects on living tissue. Did you know when graphite fiber materials burn they emit tiny needles of carbon? That is what the "smoke" is composed of, and it has unusual qualities.

There are many problems with the market penetration of carbon fiber materials and carbon sheets of graphene, which cut tissues.

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