Revolutionary 3D images have enabled researchers to understand how new anti-malaria compounds kill malaria parasites, paving the way for the next generation anti-malarial treatments.
Cell & Microbiology
May 16, 2022
0
68
An international team of researchers have discovered how a tumor-promoting kinase evolves into a GTP sensor kinase.
Molecular & Computational biology
May 2, 2022
0
95
Cancer is simultaneously one of the most common and devastating diseases in our society. So working out new ways to treat it is an enduring scientific challenge.
Biochemistry
Mar 17, 2022
0
57
The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now ...
Biochemistry
Mar 14, 2022
0
348
Cryo-EM requires protein samples to be frozen before they are imaged using an electron microscope. This revolutionary technique and its application to structural biology was the focus of the Nobel Prize for Chemistry in 2017 ...
Biotechnology
Feb 14, 2022
0
70
Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance ...
Molecular & Computational biology
Sep 28, 2021
0
52
Scientists at Sanford Burnham Prebys have identified, at an atomic level, how a part of a protein called PLEKHA7 interacts with a cell's membrane to regulate important intercellular communications.
Biochemistry
Apr 20, 2021
0
20
In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type ...
Biochemistry
Mar 29, 2021
0
21
The number of proteins in the human body, collectively known as the proteome, is vast. Somewhere between 80,000 and 400,000 proteins circulate in our cells, tissues and organs, carrying out a broad range of duties essential ...
Biochemistry
Oct 6, 2020
0
94
Lysine methylation is one of the most important covalent modifications involved in diverse cellular processes. Methylation of histone H3 Lys4 (H3K4), predominantly associated with actively transcribed genes, is mainly mediated ...
Molecular & Computational biology
Jul 22, 2020
0
2
