How host-cell enzymes combat the coronavirus

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of ...

Exploiting parasitic yeast to kill yeast pathogens

Insights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal ...

Male birth control for the malaria parasite

Disrupting two genes involved in the preservation of RNA molecules inhibits the ability of the male form of the malaria parasite to mature and be transmitted from human blood into mosquitoes, interrupting a key stage in the ...

Sleeping sickness parasite uses multiple metabolic pathways

Parasitic protozoa called trypanosomes synthesize sugars using an unexpected metabolic pathway called gluconeogenesis, according to a study published December 27 in the open-access journal PLOS Pathogens by David Horn of ...

How HIV DNA is blocked from entering the cell nucleus

Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access ...

Soil compound fights chronic wasting disease

A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a study published November 29 in the open-access journal PLOS Pathogens by Judd Aiken of the ...

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