Novel histone modifications couple metabolism to gene activity

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...

Selectively manipulating protein modifications

Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...

Gene movements observed in vivo

Certain parts of DNA are highly mobile and their dynamic motion participates in controlling gene expression. The research team working under Maria-Elena Torres-Padilla, an Inserm research director at the Institute of Genetics ...

Scientists image molecules vital for gene regulation

All the trillions of cells in our body share the same genetic information and are derived from a single, fertilized egg. When this initial cell multiplies during fetal development, its daughter cells become more and more ...

Largest, most accurate list of RNA editing sites

A research team centered at Brown University has compiled the largest and most stringently validated list of RNA editing sites in the fruit fly Drosophila melanogaster, a stalwart of biological research. Their research, which ...

The keys to a major process in DNA repair

Researchers from the Institut Jacques Monod (CNRS/University of Paris Diderot), the Institute of Biology of the Ecole Normale Supérieure (ENS/CNRS/Inserm), and the University of Bristol, have described for the first time ...

Sodium pump could act as molecular light switch

Scientists from Jülich, Grenoble, Frankfurt and Moscow uncovered the atomic structure of KR2, a light-driven transporter for sodium ions which had only recently been discovered. Based on the structural information the team ...

New findings detail structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads.

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