Revealing the biology of insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

A gallery of human RNA polymerases

Using state-of-the-art technology and techniques, EMBL's Müller group has provided the most detailed structure to date of human RNA polymerase I (Pol I), offering fundamental information about cellular function for those ...

How poxviruses multiply

The last case of smallpox worldwide occurred in Somalia in October 1977. In 1980, the World Health Organization (WHO) declared the eradication of the smallpox. According to official sources, the virus continues to exist today ...

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