Molecular Therapy is the official journal of the American Society for Gene & Cell Therapy. Available in print and online, Molecular Therapy is dedicated to publishing important peer-reviewed research and cutting-edge reviews and promoting the sciences in genetics, medicine and biotechnology.
Nanofitins, which are derived from a protein found in Sulfolobus acidocaldarius—an archaeal microorganism found in hot springs—successfully neutralized SARS-CoV-2 in mice and were well-tolerated. When inhaled by the rodents, ...
Bio & Medicine
Aug 30, 2023
0
59
Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report in the journal Molecular Therapy. As noted by the ...
Bio & Medicine
Mar 24, 2023
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49
A potential new treatment for mast cell cancers reduces the number of mast cells by "mutating" the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation. The ...
Molecular & Computational biology
Aug 10, 2021
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373
An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases ...
Bio & Medicine
May 17, 2021
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93
With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis—a debilitating and ...
Biotechnology
Feb 24, 2020
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379
A team of researchers in China has used a form of the CRISPR gene editing technique to repair a genetic defect in a viable human embryo. In their paper published in the journal Molecular Therapy, the group describes their ...
Rice University bioengineers have found new techniques for precision genome editing that are more accurate and have fewer off-target errors.
Biotechnology
Feb 8, 2016
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37
A powerful "genome editing" technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism's DNA. Now, scientists at Johns Hopkins Medicine have shown that ...
Cell & Microbiology
Jan 5, 2015
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44
Stem cells found in amniotic fluid can be transformed into a more versatile state similar to embryonic stem cells, according to a study published today in the journal Molecular Therapy. Scientists from Imperial College London ...
Cell & Microbiology
Jul 3, 2012
1
0
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...
Bio & Medicine
Apr 3, 2024
0
18
