New CRISPR-Cas9 tool edits both RNA and DNA precisely
A tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that cause many of the worst cases of meningitis.
A tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that cause many of the worst cases of meningitis.
Biotechnology
Feb 15, 2018
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377
MIT researchers have discovered a way to make bacteria more vulnerable to a class of antibiotics known as quinolones, which include ciprofloxacin and are often used to treat infections such as Escherichia coli and Staphylococcus ...
Cell & Microbiology
Dec 8, 2017
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246
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can ...
Cell & Microbiology
Apr 8, 2024
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17
RNA—in the form of messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA)—transforms the genome coded by DNA into proteins that form the backbone of all cellular functions. However, biochemical modifications ...
Cell & Microbiology
Apr 8, 2024
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25
Mitochondria are organelles that are known for providing the energy currency that fuels chemical reactions within cells, but they are also involved in other important processes vital for cell health including the innate immune ...
Molecular & Computational biology
Mar 1, 2024
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18
Are you sick and tired of getting sick and tired? A UNLV-led research team is exploring whether the reason we sometimes feel ill in the first place is because our body's cells suffer from trash that accumulates within them.
Cell & Microbiology
Feb 21, 2024
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62
A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.
Biotechnology
Feb 9, 2024
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286
Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved ...
Biotechnology
Jan 22, 2024
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81
Researchers at the University Medical Center Göttingen (UMG) have discovered a new quality control mechanism that regulates energy production in human cells. This process takes place in mitochondria, the power plants of ...
Cell & Microbiology
Jan 19, 2024
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106
One of the important breakthroughs that made it possible to program or reprogram cell fate more efficiently and with higher fidelity in a dish was discovering how to make use of a small set of molecular cowboys called pioneer ...
Cell & Microbiology
Jan 10, 2024
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29