The Journal of Medicinal Chemistry (usually abbreviated as J. Med. Chem.), is a peer-reviewed scientific journal, published since 1959 by the American Chemical Society. It was originally published as the Journal of Medicinal and Pharmaceutical Chemistry, but changed its name in 1963 to the current title. Profs. Gunda I. Georg of the University of Minnesota and Shaomeng Wang of the University of Michigan are the Editors of the journal. They took over leadership from Prof. Philip S. Portoghese of the University of Minnesota in 2012. Prof. Portoghese had served as Editor in Chief from 1972 - 2011. The Journal of Medicinal Chemistry publishes original research on the correlation of molecular structure to biological activity with a focus on the relationships of chemistry to biological activity.
Scientists at The Institute of Cancer Research, London, have created a compound that destroys a protein involved in driving cancers, including B-cell lymphoma.
Biochemistry
Apr 26, 2023
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51
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
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38
Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways. Activating those receptors opens up lung passageways, so they're a potential target for treating ...
Biochemistry
Mar 13, 2023
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26
Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of Spanish National Research Council (CSIC) have developed a series of photosensitive molecule drugs that can be reversibly activated by external light, ...
Biochemistry
Feb 16, 2023
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60
Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since cancers grow so quickly, chemotherapy ...
Biochemistry
Aug 24, 2022
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119
A study performed by researchers from the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) has discovered and synthesized several molecules that inhibit the effect ...
Biochemistry
Mar 11, 2022
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22
Researchers at the University of Toronto have created chemical compounds that can neutralize SARS-CoV-2 and several of its variants.
Biochemistry
Oct 27, 2021
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128
Thanks to our understanding of molecular biology, we have made tremendous progress in medicine, with scientists shedding light on the molecular mechanisms of several diseases. However, despite knowing how these diseases occur ...
Biochemistry
Sep 8, 2021
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40
Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of ...
Plants & Animals
Feb 9, 2021
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152
The enzyme dihydroorotate dehydrogenase (DHODH), an essential component for the de novo pyrimidine ribonucleotide biosynthesis, has reemerged in the last few years as a target for the development of small molecules with anticancer ...
Biochemistry
Apr 17, 2020
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