Activating tooth regeneration in mice

Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single set with no replacement. ...

How to change cell types by flipping a single switch

With few exceptions, cells don't change type once they have become specialized—a heart cell, for example, won't suddenly become a brain cell. However, new findings by researchers at UC Santa Barbara have identified a method ...

Researchers reconstruct early stages of embryo development

Researchers at the University of Cambridge have managed to reconstruct the early stage of mammalian development using embryonic stem cells, showing that a critical mass of cells – not too few, but not too many – is needed ...

How planarians maintain their stem cell pools over generations

Planarians are known as masters of regeneration: they can re-build any part of their bodies after amputation. This ability relies on a large number of pluripotent stem cells. To further investigate the mechanisms that enable ...

Rejuvenating the comparative approach in modern neuroscience

65 years ago, the famed behavioral endocrinologist Frank Beach wrote an article in The American Psychologist entitled 'The Snark was a Boojum'. The title refers to Lewis Carroll's poem 'The Hunting of the Snark', in which ...

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