Weaker transcription factors are better when they work together

Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...

Body part regeneration appears to be a whole-body affair

A mouse injured on one leg experiences an "awakening" of stem cells in the other leg as if the cells are preparing to heal an injury. Something similar happens in axolotls, which are masters at limb regeneration. Heart injuries ...

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