Computational 'match game' identifies potential antibiotics

Computational biologists at Carnegie Mellon University have devised a software tool that can play a high-speed "Match Game" to identify bioactive molecules and the microbial genes that produce them so they can be evaluated ...

For bacteria, the neighbors co-determine which cell dies first

Bacteria do not simply perish in hunger phases fortuitously; rather, the surrounding cells have a say as well. A research team from the Technical University of Munich (TUM) has now discovered that two factors, above all, ...

Finding a cell's true identity

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes. But in a bid to reveal ...

Breaking open the gates of antibiotic resistance

Antibiotic resistance is a major health threat, with about two million people in the US getting an antibiotic-resistant infection per year, according to the Centers for Disease Control and Prevention (CDC). Gram negative ...

Understanding circadian rhythms in algae and fungi

Fungi, algae, and cyanobacteria might not complain about jet lag. But like humans, their physiologies adhere to a roughly 24-hour cycle of behavioral patterns in the absence of external cues. Organisms that experience recurring ...

Elucidating cellular responses to force

Accumulated evidence suggests that physical force plays an important role in developmental processes of fertilized animal eggs. During embryogenesis, a variety of cell populations actively migrate and change their positions, ...

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