To ward off aging, stem cells must take out the trash

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells ...

Research team establishes cell lines to improve iPSC research

Induced Pluripotent Stem Cell (iPSC) lines have become essential for determining the underlying genetic drivers of human disease. Genomes of iPSCs can be easily edited using the bacteria-based CRISPR/Cas9 technology to introduce ...

Blood stem cells found to not be in charge in an emergency

As long as we are healthy, our body keeps the number of blood and immune cells largely constant. However, any infection or other disorder that increases cell consumption results in cell loss, which must be replaced as quickly ...

New advances in stem-cell derived mouse embryo model

Just two weeks after announcing the development of a mouse embryo model, complete with beating hearts and the foundations for a brain and other organs, from mouse stem cells, researchers in the laboratory of Magdalena Zernicka-Goetz, ...

Stem cell biologists create new human cell type for research

Professor Vincent Pasque and his team at KU Leuven have managed to generate a new type of human cell in the lab using stem cells. The new cells closely resemble their natural counterparts in early human embryos. As a result, ...

How intestine replaces and repairs itself

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine's resident stem cells are responsible ...

The beginning of life: The early embryo is in the driver's seat

One often thinks that the early embryo is fragile and needs support. However, at the earliest stages of development, it has the power to feed the future placenta and instructs the uterus so that it can nest. Using blastoids, ...

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