Cell Stem Cell is a broad-spectrum journal that covers the entire spectrum of stem cell biology. Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue-specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem-cell-based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource-based innovations. We will consider studies from any model system that provides insights into stem cell biology, and we encourage submissions on human stem cells.
Stem cell clues uncovered
Proper tissue function and regeneration is supported by stem cells, which reside in so-called niches. New work from Carnegie's Yixian Zheng and Haiyang Chen identifies an important component for regulating stem cell niches, ...
Jul 12, 2013
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Salk scientists discover more versatile approach to creating stem cells
Stem cells are key to the promise of regenerative medicine: the repair or replacement of injured tissues with custom grown substitutes. Essential to this process are induced pluripotent stem cells (iPSCs), which can be created ...
Efficient model for generating human iPSCs developed
Researchers at the University of California, San Diego School of Medicine report a simple, easily reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem ...
Minimizing the cellular contaminants that plague the differentiation of pluripotent stem cells
Embryonic stem cells (ESCs) have the potential to form more than 200 distinct cell types in the human body. Although ESCs can differentiate into any specialized tissue, scientists are still unsure of how to coax these pluripotent ...
Researchers challenge long-held assumption of gene expression in embryonic stem cells
Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self-renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers. ...
Scientists made fundamental discovery about how properties of embryonic stem cells controlled
The study, which focuses on the process by which these cells renew and increase in number, could help research to find new treatments.
Researchers succeed in making generations of mouse clones
Using the technique that created Dolly the sheep, researchers from the RIKEN Center for Developmental Biology in Kobe, Japan have identified a way to produce healthy mouse clones that live a normal lifespan and can be sequentially ...
Turn out the light: 'Switch' determines cancer cell fate
(Phys.org) —Like picking a career or a movie, cells have to make decisions – and cancer results from cells making wrong decisions.
Histones may hold the key to the generation of totipotent stem cells
One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation ...
Scientists succeed in manipulating stem cells into liver and pancreas precursor cells
Scientists from the Genome Institute of Singapore (GIS) in A*STAR have developed a novel method of directing human pluripotent stem cells (hPSCs) into highly pure populations of endoderm, a valuable cell type that gives rise ...
