Cell Stem Cell is a broad-spectrum journal that covers the entire spectrum of stem cell biology. Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue-specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem-cell-based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource-based innovations. We will consider studies from any model system that provides insights into stem cell biology, and we encourage submissions on human stem cells.
New reprogramming factor cocktail produces therapy-grade induced pluripotent stem cells
Induced pluripotent stem cells (iPSCs)—adult cells reprogrammed back to an embryonic stem cell-like state—may hold the potential to cure damaged nerves, regrow limbs and organs, and perfectly model a patient's particular ...
Sep 04, 2014
in
The intestine has a reservoir of stem cells that are resistant to chemotherapy
The intestine has a high rate of cellular regeneration due to the wear and tear originated by its function degrading and absorbing nutrients and eliminating waste. The entire cell wall is renewed once a week approximately. ...
How RNA could keep us young
With over 75 million baby boomers in the U.S. alone, age-related diseases are a major concern in the health care system. The connection between aging and cancer has become a pillar in medicine: we know that as we age, our ...
Factor found to balance medically useful stem cell qualities
A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.
Flow of cerebrospinal fluid regulates division
Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper scientists have discovered that the flow of cerebrospinal fluid is a key signal for neural ...
New tool for efficiently validating the accuracy of CRISPR-Cas9 reactions
CRISPR-Cas9's popularity continues to grow ever since its first use in genome editing in January, 2013. What makes CRISPR-Cas9 so remarkable is its astonishing efficiency and availability; relatively speaking, it is easy ...
Two proteins safeguard skin stem cells
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days. A study led by ICREA ...
Quest for new medicines could be helped by cell discovery
Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.
Purifying cells to treat disease
Various cell therapies involve injecting a specific cell type into a patient. These include, for example, bone marrow transplants and some types of immunotherapy that use T-cells (a white blood cell involved in immunity) ...
Original cell type does not affect iPS cell differentiation to blood
The effectiveness of reprogramming cells into blood cells is thought to depend on the original cell type and reprogramming method. Researchers at CiRA show this assumption is actually the result of epigenetic effects, suggesting ...
