Samumed to announce potential disease modifying treatment of osteoarthritis at ACR 2015

Nov. 3, 2015—Samumed, LLC, a leader in tissue regeneration, announced today that it will present preclinical and clinical data on a small molecule modulator of the Wnt pathway (SM04690, an investigational new drug) for potential disease modifying treatment of osteoarthritis (OA) of the knee at 2015 American College of Rheumatology Annual Meeting.

Specifically, Samumed will present preclinical research results that demonstrate cartilage regeneration in an animal model of OA after a single intra-articular injection of SM04690 in an oral presentation. In addition, Samumed will present two posters that detail interim safety, pK, efficacy and radiographic imaging results (MRI and X-ray), respectively, from a now-completed 24-week placebo-controlled, double-blind, randomized Phase I clinical trial of SM04690 in patients with moderate to severe osteoarthritis of the knee.

"Our technology platform focuses on small molecule drugs that repair/regenerate local tissue. To date, we have four compounds in clinical trials, targeting five disease areas that impact the health and quality-of-life of millions of people. We will continue to expand our pipeline, as well as share data from our programs with the scientific and medical community," said Osman Kibar, Ph.D., Chief Executive Officer and Founder of Samumed.

Provided by Rasky Baerlein Strategic Communications