Amino-functionalized carbon nanotubes act as a carrier for nerve growth factor

April 21st, 2014
Amino-functionalized carbon nanotubes act as a carrier for nerve growth factor
Under inverted fluorescence microscope, the multi-walled carbon nanotubes-ethylenediamine-nerve growth factor complexes significantly induce PC12 cell differentiation, and the growing protuberances are long, dense, and woven into meshes (× 200). Credit: Neural Regeneration Research
In recent years, there are growing studies concerning the use of different carrier materials for sustained-release and controlled-release of nerve growth factor in neuroscience research.

In a study by Prof. Gao Li and team from Tongji Medical College, Huazhong University of Science and Technology in China, amino-functionalized ethylenediamine-treated multi-walled carbon nanotubes were used to prepare carbon nanotubes-nerve growth factor complexes by non-covalent grafting. Results showed that amino functionalization improved carbon nanotubes-nerve growth factor complex dispersibility, reduced their toxicity to PC12 cells, and promoted PC12 cell differentiation and chick embryo dorsal root ganglion.

This study has been reported in the Neural Regeneration Research (Vol. 9, No. 3, 2014).

Provided by Neural Regeneration Research

This Phys.org Science News Wire page contains a press release issued by an organization mentioned above and is provided to you “as is” with little or no review from Phys.Org staff.

More news stories

Chikungunya fever identified in the United States

(HealthDay)—Chikungunya fever is being seen in travelers returning to the United States from affected regions and should be considered as a diagnosis for febrile travelers, according to an ideas and opinions ...

Big new iPhone brings Apple more profit

Apple's largest iPhone is selling for $100 more than its other new model, but a new report says it costs Apple only $15.50 more to make the more expensive version.

Joint effort in standardizing due date estimation

(HealthDay)—The American College of Obstetricians and Gynecologists, the American Institute of Ultrasound in Medicine, and the Society for Maternal-Fetal Medicine have jointly released new recommendations ...