This Science News Wire page contains a press release issued by an organization and is provided to you "as is" with little or no review from Science X staff.

Optimal distance between 2 electrode tips when recording compound nerve action potentials

April 2nd, 2014
Optimal distance between 2 electrode tips when recording compound nerve action potentials
This shows the different approaches to compound nerve action potential recording. Both ends of the median nerve had electrodes placed, leaving the middle part of approximately 4𔃃 mm intact. The two electrodes were placed under both ends of the nerve trunk, distal and proximal to the middle. The ground wire was inserted into the muscle close to the intact part (Method A; n = 10). In Method B (n = 10), the median nerve was completely dissociated, then otherwise treated as in Method A. In the third approach, the ground wire was placed beneath the middle part of the completely dissociated median nerve trunk (Method C; n = 10). Sti: Stimulating electrodes; Rec: recording electrodes; Gnd: ground wire. Credit: Neural Regeneration Research

The distance between the two electrode tips can greatly influence the parameters used for recording compound nerve action potentials. To investigate the optimal parameters for these recordings in the rat median nerve, Prof. Jie Lao and colleagues from HuaShan Hospital, Fudan University in China dissociated the nerve using different methods and compound nerve action potentials were orthodromically or antidromically recorded with different electrode spacings. Compound nerve action potentials could be consistently recorded using a method in which the middle part of the median nerve was intact, with both ends dissociated from the surrounding fascia and a ground wire inserted into the muscle close to the intact part.

A distance of 5 mm between recording and stimulating electrodes and a distance of 10 mm between recording and stimulating sites were found to be optimal for compound nerve action potential recording in the rat median nerve. In addition, the orthodromic compound action potential, with a biphasic waveform that was more stable and displayed less interference (however also required a higher threshold and higher supramaximal stimulus), was found to be superior to the antidromic compound action potential.

More information:
Li YP, Lao J, Zhao X, Tian D, Zhu Y, Wei XC. The optimal distance between two electrode tips during recording of compound nerve action potentials in the rat median nerve. Neural Regen Res. 2014;9(2):171-178.

Provided by Neural Regeneration Research

Citation: Optimal distance between 2 electrode tips when recording compound nerve action potentials (2014, April 2) retrieved 28 March 2024 from https://sciencex.com/wire-news/157893557/optimal-distance-between-2-electrode-tips-when-recording-compoun.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.