News tagged with zinc fingers
Rapid method of assembling new gene-editing tool could revolutionize genetic research
Development of a new way to make a powerful tool for altering gene sequences should greatly increase the ability of researchers to knock out or otherwise alter the expression of any gene they are studying. The new method ...
Apr 09, 2012 |
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Researchers create first targeted knockout rats using zinc finger nuclease technology
Scientists from The Medical College of Wisconsin in Milwaukee, Sangamo Biosciences, Inc., Sigma-Aldrich Corporation, Open Monoclonal Technology, Inc. (OMT) and INSERM today announced the creation of the first genetically ...
Jul 23, 2009 |
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Genome editing, a next step in genetic therapy, corrects hemophilia in animals
Using an innovative gene therapy technique called genome editing that hones in on the precise location of mutated DNA, scientists have treated the blood clotting disorder hemophilia in mice. This is the first time that genome ...
Jun 26, 2011 |
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Scientists track variant of gene-regulating protein in embryonic stem cells
(PhysOrg.com) -- The path to fully developed cells from embryonic stem cells requires that the right genes are turned on and off at the right times. New research from Rockefeller University shows that tiny ...
Mar 10, 2010 |
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Technique enables efficient gene splicing in human embryonic stem cells
A novel technique allows researchers to efficiently and precisely modify or introduce genes into the genomes of human embryonic stem cells (ESCs) and induced pluripotent stem (iPS) cells, according to Whitehead scientists. ...
Aug 13, 2009 |
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Researchers develop faster method of engineering zinc-finger nucleases
A team led by Massachusetts General Hospital (MGH) researchers has developed a faster way to engineer synthetic enzymes that target specific DNA sequences for inactivation, repair or alteration. The report from the MGH Molecular ...
Dec 12, 2010 |
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Transcription factors guide differences in human and chimp brain function
Humans share at least 97 percent of their genes with chimpanzees, but, as a new study of transcription factors makes clear, what you have in your genome may be less important than how you use it.
Dec 07, 2009 |
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Researcher develop new technique for modifying plant genes
Researchers at the University of Minnesota and Massachusetts General Hospital have used a genome engineering tool they developed to make a model crop plant herbicide-resistant without significant changes to its DNA.
Apr 29, 2009 |
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A question of gene silencing
When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...
Aug 24, 2011 |
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Protein interaction network can respond Helicobacter pylori infection?
Helicobacter pylori (H pylori) is a gram negative bacterium which infects about 50% of the world population. H pylori colonization causes a strong systemic immune response. Various tools have been employed to identify the rela ...
Medicine & Health / Medical research
Oct 16, 2009 |
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The structure-based design of zinc finger nucleases can facilitate genomic editing
A recent study carried out at the State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China-Research, and published in the May 2011 issue of Science China Life Sciences (Issue 54) de ...
May 20, 2011 |
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