NYU Langone yeast geneticists report they have developed a novel tool—dubbed "the telomerator"—that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed ...
Biotechnology
Nov 3, 2014
2
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An international team of scientists led by Jef Boeke, PhD, director of NYU Langone Medical Center's Institute for Systems Genetics, has synthesized the first functional chromosome in yeast, an important step in the emerging ...
Cell & Microbiology
Mar 27, 2014
25
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Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions. ...
Cell & Microbiology
Jan 29, 2012
0
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In the quest to understand genomes -- how they're built, how they're organized and what makes them work -- a team of Johns Hopkins researchers has engineered from scratch a computer-designed yeast chromosome and incorporated ...
Cell & Microbiology
Sep 14, 2011
29
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Scientists at Penn State University have achieved a major milestone in the attempt to assemble, in a test tube, entire chromosomes from their component parts. The achievement reveals the process a cell uses to package the ...
Cell & Microbiology
May 19, 2011
0
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Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains.
Cell & Microbiology
Nov 8, 2023
0
19
When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in ...
Cell & Microbiology
May 26, 2023
0
83
Biotechnologists at Delft University of Technology have built an artificial chromosome in yeast. The chromosome can exist alongside natural yeast chromosomes, and serves as a platform to safely and easily add new functions ...
Biotechnology
Jan 11, 2021
0
429
Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism. Now, researchers from Japan have identified mechanisms that choose between alternate pathways of DNA repair to ...
Evolution
Apr 30, 2020
0
17
ETH researchers studying yeast cells have discovered a new mechanism for detecting foreign genetic material from pathogens or environmental contamination, and rendering it harmless.
Cell & Microbiology
Oct 11, 2018
0
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