The Wnt signaling pathway, a system present in living organisms, plays a pivotal role in cell growth, differentiation, and migration. It has a long history dating back to 1982, when the first Wnt gene, essential for cellular ...
Cell & Microbiology
Nov 6, 2023
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6
Wnt signaling is a well-known mode of cell-to-cell communication in multicellular biological organisms. It involves the secretion of small Wnt glycoproteins, by signaling cells, that bind to receptor proteins in the membrane ...
Molecular & Computational biology
Aug 3, 2023
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66
Cells in humans and other vertebrates, as well as invertebrates, have signaling pathways that play essential roles in embryo development, cell proliferation and tissue structuring. Dysregulation in one of these signaling ...
Cell & Microbiology
Mar 18, 2019
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106
How cells in developing embryos communicate depends a great deal on context, according to scientists at Rice University.
Cell & Microbiology
Mar 1, 2019
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47
Tiny microscopic worms, invisible to the naked eye, are helping scientists to better understand an extraordinarily complex biological pathway that connects fat to overall health and aging in humans.
Cell & Microbiology
Nov 13, 2018
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82
Signaling molecules of the Wnt family are ubiquitous in biology. From cnidaria to man, they are responsible for forming the basic shape of all organisms. Without Wnt, our body would not have a top or bottom, front or rear. ...
Cell & Microbiology
Nov 20, 2015
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19
A signaling pathway once thought to have little if any role during embryogenesis is a key player in the formation of the front-most portion of developing vertebrate embryos. Moreover, signals emanating from this region—referred ...
Cell & Microbiology
Jul 17, 2014
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0
In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar ...
Cell & Microbiology
May 6, 2014
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0
In a paper published in this week's Online Early Edition of the Proceedings of the National Academy of Sciences, researchers from the University of California, San Diego School of Medicine identify a key gene receptor and ...
Cell & Microbiology
Jan 13, 2014
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0
Researchers reveal a new way in which cells restrain beta-catenin and potentially suppress tumor metastasis: the protein can be ejected from cells in small vesicles called exosomes. The study appears online on September 13 ...
Cell & Microbiology
Sep 13, 2010
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